Patents Assigned to ALEMBIC PHARMACEUTICALS LIMITED
  • Solid state forms of Venetoclax and its process for the preparation there of
    Patent number: 11613540
    Abstract: The present invention provides solid state forms of Venetoclax, particularly relates to novel alkali metal salt and/or DMF solvate form of Venetoclax or its salt. The present invention also relates to process for the preparation Venetoclax by using the said solid state form of Venetoclax.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: March 28, 2023
    Assignee: Alembic Pharmaceuticals Limited
    Inventors: Vittal Tvsk, Dinesh Chudasama, Saisuryanarayana Donthukurthi, Tejas Shah, Chetan Patil, Mahendar Velisoju, Mahender Rao Siripragada
  • An Improved Process Of Preparation Of Ivosidenib
    Publication number: 20220324838
    Abstract: The present invention relates to an improved process of preparation of Ivosidenib a compound of Formula (I). More particularly, present invention provides process of preparation of intermediates. Also provide process of preparation of amorphous form of Ivosidenib. Further, present invention provides process of preparation of chirally pure Ivosidenib a compound of Formula (I).
    Type: Application
    Filed: August 6, 2020
    Publication date: October 13, 2022
    Applicant: Alembic Pharmaceuticals Limited
    Inventors: Vittal Tvsk, Sanjiv Tomer, Kamlesh Kanzariya, Harsh Patel
  • Pharmaceutical Composition Comprising Venetoclax
    Publication number: 20220211725
    Abstract: The present subject matter provides amorphous solid dispersions of venetoclax or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising said amorphous solid dispersions. The present subject matter also provides methods for the preparation of said solid dispersions and compositions. The present subject matter further provides pharmaceutical compositions comprising mixture of solid dispersions.
    Type: Application
    Filed: May 6, 2020
    Publication date: July 7, 2022
    Applicant: Alembic Pharmaceuticals Limited
    Inventors: Pankaj Kumar Khapra, Rahul Dabre, Prasanna Barada Sahoo, Murthy V.S.N. Dwibhashyam
  • Bioavailable Oral Dosage Form Of Tyrosine-Kinase Inhibitor
    Publication number: 20220175774
    Abstract: A pharmaceutically acceptable composition comprising an effective amount of a dasatinib or a pharmaceutically acceptable salt thereof, and a binder, one or more diluent or mixture thereof, a disintegrant, a lubricant, wherein said composition is devoid of dasatinib hydrate or solvate or any crystalline polymorph, wherein the dasatinib or a pharmaceutically acceptable salt thereof, is present in an amorphous form.
    Type: Application
    Filed: December 6, 2021
    Publication date: June 9, 2022
    Applicant: Alembic Pharmaceuticals Limited
    Inventors: Barada Prasanna Sahoo, Naveen Kumar Midathanapally, Rahul Sudhakar Dabre, Pankaj Kumar Khapra
  • Solid State Forms Of Venetoclax And Its Process For The Preparation There Of
    Publication number: 20210130350
    Abstract: The present invention provides solid state forms of Venetoclax, particularly relates to novel alkali metal salt and/or DMF solvate form of Venetoclax or its salt. The present invention also relates to process for the preparation Venetoclax by using the said solid state form of Venetoclax.
    Type: Application
    Filed: January 5, 2021
    Publication date: May 6, 2021
    Applicant: Alembic Pharmaceuticals Limited
    Inventors: Vittal Tvsk, Dinesh Chudasama, Saisuryanarayana Donthukurthi, Tejas Shah, Chetan Patil, Mahendar Velisoju, Mahender Rao Siripragada
  • Solid state forms of venetoclax and its process for the preparation there of
    Patent number: 10934289
    Abstract: The present invention provides solid state forms of Venetoclax, particularly relates to novel alkali metal salt and/or DMF solvate form of Venetoclax or its salt. The present invention also relates to process for the preparation Venetoclax by using the said solid state form of Venetoclax.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: March 2, 2021
    Assignee: Alembic Pharmaceuticals Limited
    Inventors: Vittal Tvsk, Dinesh Chudasama, Saisuryanarayana Donthukurthi, Tejas Shah, Chetan Patil, Mahendar Velisoju, Mahender Rao Siripragada
  • Solid State Forms Of Venetoclax And Its Process For The Preparation There Of
    Publication number: 20200354361
    Abstract: The present invention provides solid state forms of Venetoclax, particularly relates to novel alkali metal salt and/or DMF solvate form of Venetoclax or its salt. The present invention also relates to process for the preparation Venetoclax by using the said solid state form of Venetoclax.
    Type: Application
    Filed: January 29, 2019
    Publication date: November 12, 2020
    Applicant: Alembic Pharmaceuticals Limited
    Inventors: Vittal Tvsk, Dinesh Chudasama, Saisuryanarayana Donthukurthi, Tejas Shah, Chetan Patil, Mahendar Velisoju, Mahender Rao Siripragada
  • Polymorph of Riociguat and its process for the preparation
    Patent number: 10414766
    Abstract: The present invention relates to novel polymorph of riociguat and process for preparing the polymorph. The present invention also relates to the improved process for the preparation of riociguat.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: September 17, 2019
    Assignee: ALEMBIC PHARMACEUTICALS LIMITED
    Inventors: Mahender Rao Siripragada, Mahendar Velisoju, Tejas Shah, Chetan Patil, Kalpesh Jadav, Ashvinkumar Bhuva, Saisuryanaraya Donthukurthi
  • Process and novel polymorphic form of Apremilast
    Patent number: 10399942
    Abstract: The present invention provides an improved process for the preparation of Apremilast using novel intermediates. The present invention also relates to the novel crystalline polymorphic form of Apremilast.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: September 3, 2019
    Assignee: Alembic Pharmaceuticals Limited
    Inventors: Mahender Rao Siripragada, Dinesh Panchasara, Ilesh Patel, Bhavesh Prajapati, Ankit Shah, Ananda Babu Thirunavakarasu, Pinky Parikh
  • IMPROVED PROCESS AND NOVEL POLYMORPHIC FORM OF APREMILAST
    Publication number: 20180327356
    Abstract: The present invention provides an improved process for the preparation of Apremilast using novel intermediates. The present invention also relates to the novel crystalline polymorphic form of Apremilast.
    Type: Application
    Filed: July 29, 2016
    Publication date: November 15, 2018
    Applicant: Alembic Pharmaceuticals Limited
    Inventors: Mahender Rao Siripragada, Dinesh Panchasara, Ilesh Patel, Bhavesh Prajapati, Ankit Shah, Ananda Babu Thirunavakarasu, Pinky Parikh
  • STABLE PHARMACEUTICAL COMPOSITION OF ALOGLIPTIN AND METFORMIN FIXED DOSE COMBINATION
    Publication number: 20180235911
    Abstract: The present invention relates to a solid oral preparations comprising alogliptin and metformin fixed dose combination and to a process for preparation thereof. More particularly, it relates to a solid oral preparation of alogliptin and metformin fixed dose combination formulation which is stable and easy to manufacture.
    Type: Application
    Filed: August 20, 2016
    Publication date: August 23, 2018
    Applicant: ALEMBIC PHARMACEUTICALS LIMITED
    Inventors: Dr. Pankaj KHAPRA, Hitesh Vaikunthbhai THAKKAR, Subhajit Chandra KAR
  • Process for the preparation of vilazodone hydrochloride and its amorphous form
    Patent number: 9969721
    Abstract: The present invention relates to an improved process for the preparation of vilazodone Hydrochloride and a process for preparation of novel pure amorphous form of vilazodone hydrochloride.
    Type: Grant
    Filed: April 5, 2013
    Date of Patent: May 15, 2018
    Assignee: Alembic Pharmaceuticals Limited
    Inventors: Venkat Raman Jayaraman, Dhiraj Rathod, Irfan Vohra, Vinayak Bhujade, Viral Modi, Mayur Budh, Ojas Gandhi
  • NOVEL POLYMORPHIC FORMS OF VORTIOXETINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
    Publication number: 20170189394
    Abstract: The present invention provides polymorphic forms of Vortioxetine of and its pharmaceutically acceptable salts. Specifically the present invention relates to the novel crystalline forms of Vortioxetine or its pharmaceutically acceptable salts. Moreover, the present invention also provides an amorphous form of Vortioxetine hydrobromide and a stable amorphous co-precipitate of Vortioxetine hydrobromide with pharmaceutically acceptable excipients.
    Type: Application
    Filed: April 21, 2015
    Publication date: July 6, 2017
    Applicant: ALEMBIC PHARMACEUTICALS LIMITED
    Inventors: Venkat Raman Jayaraman, Sanjiv Tomer, Piyush Rana, Kamlesh Kanzariya, Sunit Kumar, Nilav Patel, Manoj Borsaniya, Sudhir Shah, Anand Thirunavakarasu
  • Process for the preparation of vilazodone hydrochloride and its amorphous form
    Patent number: 9493443
    Abstract: The present invention relates to an improved process for the preparation of vilazodone hydrochloride and a process for preparation of novel pure amorphous form of vilazodone hydrochloride.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: November 15, 2016
    Assignee: Alembic Pharmaceuticals Limited
    Inventors: Venkat Raman Jayaraman, Dhiraj Rathod, Irfan Vohra, Vinayak Bhujade, Viral Modi, Mayur Budh, Ojas Gandhi
  • Reference markers for fesoterodine fumarate
    Patent number: 9440910
    Abstract: The present invention relates to the new impurities of Fesoterodine, Fesoterodine symmetric dimer impurity and asymmetric dimer impurity, process for preparing and isolating thereof. The invention also deals with analytical standards and analytical methods used for the control of the production process and final quality of Fesoterodine.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: September 13, 2016
    Assignee: Alembic Pharmaceuticals Limited
    Inventors: Venkatraman Jayaraman, Sundara Kalyana Balaji, Samir Patel, Thakor Indrajit, Viral Parekh, Mahesh Ladani, Chetan Patil, Ronak Patel, Darshan Parmar
  • PROCESS FOR THE PREPARATION OF VILAZODONE HYDROCHLORIDE AND ITS AMORPHOUS FORM
    Publication number: 20150239871
    Abstract: The present invention relates to an improved process for the preparation of vilazodone hydrochloride and a process for preparation of novel pure amorphous form of vilazodone hydrochloride.
    Type: Application
    Filed: April 6, 2015
    Publication date: August 27, 2015
    Applicant: ALEMBIC PHARMACEUTICALS LIMITED
    Inventors: Venkat Raman Jayaraman, Dhiraj Rathod, Irfan Vohra, Vinayak Bhujade, Viral Modi, Mayur Budh, Ojas Gandhi
  • Process for preparing fesoterodine
    Patent number: 9085509
    Abstract: The present invention relates to an improved process for the preparation of Fesoterodine and pharmaceutically acceptable salts thereof. The present invention particularly relates to a process for the preparation of fesoterodine and pharmaceutically acceptable salts thereof which involves use and preparation of R(+)benzyl tolterodine and fumarate salt of R(+)-[4-benzyloxy-3-(3-diisopropylamino-1-phenylpropyl)-phenyl]-methanol.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: July 21, 2015
    Assignee: ALEMBIC PHARMACEUTICALS LIMITED
    Inventors: Jayaraman Venkat Raman, Samir Patel, Indrajit Thakor, Mahesh Ladani, Chetan Patil, Ronak Patel, Prashant Raval, Viral Parekh, Hiral Shah
  • THE NOVEL REFERENCE MARKERS FOR FESOTERODINE FUMARATE
    Publication number: 20150175526
    Abstract: The present invention relates to the new impurities of Fesoterodine, Fesoterodine symmetric dimer impurity and asymmetric dimer impurity, process for preparing and isolating thereof. The invention also deals with analytical standards and analytical methods used for the control of the production process and final quality of Fesoterodine.
    Type: Application
    Filed: January 8, 2013
    Publication date: June 25, 2015
    Applicant: Alembic Pharmaceuticals Limited
    Inventors: Venkatraman Jayaraman, Sundara Kalyana Balaji, Samir Patel, Thakor Indrajit, Viral Parekh, Mahesh Ladani, Chetan Patil, Ronak Patel, Darshan Parmar, Venkatraman Jayaraman, Sundara Kalyana Balaji, Samir Patel, Thakor Indrajit, Viral Parekh, Mahesh Ladani, Chetan Patil, Ronak Patel, Darshan Parmar
  • PROCESS FOR THE PREPARATION OF VILAZODONE HYDROCHLORIDE AND ITS AMORPHOUS FORM
    Publication number: 20150087835
    Abstract: The present invention relates to an improved process for the preparation of vilazodone Hydrochloride and a process for preparation of novel pure amorphous form of vilazodone hydrochloride.
    Type: Application
    Filed: April 5, 2013
    Publication date: March 26, 2015
    Applicant: ALEMBIC PHARMACEUTICALS LIMITED
    Inventors: Venkat Raman Jayaraman, Dhiraj Rathod, Irfan Vohra, Vinayak Bhujade, Viral Modi, Mayur Budh, Ojas Gandhi
  • PROCESS FOR PREPARING FESOTERODINE
    Publication number: 20140039216
    Abstract: The present invention relates to an improved process for the preparation of Fesoterodine and pharmaceutically acceptable salts thereof. The present invention particularly relates to a process for the preparation of fesoterodine and pharmaceutically acceptable salts thereof which involves use and preparation of R(+)benzyl tolterodine and fumarate salt of R(+)-[4-benzyloxy-3-(3-diisopropylamino-1-phenylpropyl)-phenyl]-methanol.
    Type: Application
    Filed: November 11, 2011
    Publication date: February 6, 2014
    Applicant: ALEMBIC PHARMACEUTICALS LIMITED
    Inventors: Jayaraman Venkat Raman, Samir Patel, Indrajit Thakor, Mahesh Ladani, Chetan Patil, Ronak Patel, Prashant Raval, Viral Parekh, Hiral Shah