Abstract: A modulated Class E transmitter is disclosed. In one embodiment of the invention, the modulated Class E oscillator achieves high coil currents (˜1 A) and voltages (˜500V) with low power components by precisely timed injection of current when the oscillating current in the inductor passes through zero. A detector circuit is used to trigger the current injection at the appropriate instant regardless of changes in the resonant frequency of the system. Its phase can be adjusted to compensate for propagation delays in the drive circuitry, while amplitude modulation is accomplished by switching in additional reactive conductance to increase the current injected into the tank circuit. Frequency modulation is accomplished in an alternate embodiment.

Abstract: Many diseases are related to variations in the genetically specified structure of proteins synthesized by cells. Genetic engineering is now able to identify the structural variations and to introduce new genes to synthesize more healthful proteins, but it is difficult actually to identify the specific protein or chemical variants in bodily fluids and extracts of tissues in order to diagnose diseases and to assess the effects of treatment. This invention provides apparatuses and methods which allow a user to finely discriminate between small variations in the structure, function and levels of specific biochemicals even when admixed with other biochemicals.

Abstract: A modulated Class E transmitter is disclosed. In one embodiment of the invention, the modulated Class E oscillator achieves high coil currents (˜1A) and voltages (˜500V) with low power components by precisely timed injection of current when the oscillating current in the inductor passes through zero. A detector circuit is used to trigger the current injection at the appropriate instant regardless of changes in the resonant frequency of the system. Its phase can be adjusted to compensate for propagation delays in the drive circuitry, while amplitude modulation is accomplished by switching in additional reactive conductance to increase the current injected into the tank circuit.

Abstract: Systems and methods for obtaining images of body organs or other tissue for each of their multiple characterizing aspects, and for classifying different tissue types within the images according to their characterizing aspects, are disclosed herein. The tissue may be irradiated with an ultrasonic signal, and an interaction signal received in return. Sinogram data may be constructed from the received interaction signal, and multiple characterizing data extracted therefrom. The multiple characterizing data representing multiple characterizing aspects may then be matched to tissue type within a database containing information correlating characterizing multi-aspect data with tissue type. Images of the tissue may then be presented with identifiers associating tissue portions with their matched tissue types.

Abstract: A system for evaluating the cardiovascular system parameters using indicator dilution and non-invasive or minimally invasive detection methods is disclosed. Intravascular indicators are stimulated, and emission patterns detected for computation of cardiac output, cardiac index, blood volume and other indicators of cardiovascular health.

Abstract: A receptacle for supporting a breast during ultrasonic scanning. The receptacle may include a contoured cup made of material that is substantially transparent to acoustical energy and have an open end into which the breast may be inserted and a narrowed end to receive a nipple of the breast. The receptacle may include spaced-apart elongated members, each made of material that is not substantially transparent to acoustical energy and each being mechanically coupled to the open end and to the narrow end of the cup. A fluid pump, impedance matching and a contoured tabletop are also disclosed.

Abstract: Spinal cord injury and other injuries and diseases of the nervous system often result in the inability to sense the need to empty the rectum or to control the timing of bowel movements. This invention includes microminiature electronic devices implanted on or around the large bowel to sense the volume and nature of rectal contents and to stimulate peristaltic contractions to empty the large bowel when it is convenient for the patient to do so.

Abstract: A method and apparatus for conditioning muscles during sleep. The apparatus includes microminiature electrical stimulators that are injected into the muscles to be exercised and a system of transmission coils located in or on the mattress of a bed. The transmission coils transmit power and command signals to the implanted electrical stimulators while the patient sleeps or rests. The implanted electrical stimulators can be programmed so as to produce the desired pattern of muscle exercise without producing cutaneous sensations that would disturb the patient.

Abstract: Determining the placement of an endotracheal tube in a patient. The invention evaluates discontinuities in the medium surrounding the endotracheal tube, such as the airway, as a function of distance past an end of the endotracheal tube. Using a loudspeaker to generate sound waves, the sound waves propagate through a coiled wavetube, a connecting adapter, and an endotracheal tube, into the area of interest. With a processing system, reflected sound waves which return from the cavity back to a microphone within the wavetube are analyzed and an area-distance curve of the area in interest is constructed.

Abstract: A modulated Class E transmitter is disclosed. In one embodiment of the invention, the modulated Class E oscillator achieves high coil currents (˜1A) and voltages (˜500V) with low power components by precisely timed injection of current when the oscillating current in the inductor passes through zero. A detector circuit is used to trigger the current injection at the appropriate instant regardless of changes in the resonant frequency of the system. Its phase can be adjusted to compensate for propagation delays in the drive circuitry, while amplitude modulation is accomplished by switching in additional reactive conductance to increase the current injected into the tank circuit. Frequency modulation is accomplished in an alternate embodiment.