Patents Assigned to Algos Pharmaceutical Corporation
  • Anticonvulsant containing composition for treating neuropathic pain
    Patent number: 6187338
    Abstract: The analgesic effectiveness of tramadol is significantly enhanced by administering tramadol prior to, with or following the administration of an analgesia enhancer which is a nontoxic NMDA receptor blocker and/or a nontoxic substance that blocks at least one major intracellular consequence of NMDA receptor activation.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: February 13, 2001
    Assignee: Algos Pharmaceutical Corporation
    Inventors: Frank S. Caruso, Fredrick L. Minn, John W. Lyle
  • Analgesic composition and method for alleviating pain
    Patent number: 6054451
    Abstract: The analgesic effectiveness of an analgesic selected from the group consisting of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine, (S)-5-(2-azetidinylmethoxy)-2-chloropyridine and pharmaceutically acceptable salts thereof is significantly potentiated by administering an analgesic-potentiating amount for said analgesic of at least one nontoxic NMDA receptor antagonist.
    Type: Grant
    Filed: April 21, 1998
    Date of Patent: April 25, 2000
    Assignee: Algos Pharmaceutical Corporation
    Inventor: Frank S. Caruso
  • Method and composition for treating migraine
    Patent number: 6043244
    Abstract: This invention relates to methods and compositions for the treatment of migraine headache by administering a combination of a) a migraine-treating amount of an ergot alkaloid and b) an antimigraine-potentiating amount of at least one of dextromethorphan or dextrorphan.
    Type: Grant
    Filed: January 7, 1999
    Date of Patent: March 28, 2000
    Assignee: Algos Pharmaceutical Corporation
    Inventor: Frank S. Caruso
  • Analgesic composition and method for treating pain
    Patent number: 6007841
    Abstract: The analgesic effectiveness of a narcotic agonist-antagonist analgesic is significantly potentiated by administering a narcotic agonist-antagonist analgesic together with at least one nontoxic NMDA receptor antagonist.
    Type: Grant
    Filed: March 13, 1998
    Date of Patent: December 28, 1999
    Assignee: Algos Pharmaceutical Corporation
    Inventor: Frank S. Caruso
  • Method for treating a migraine
    Patent number: 5939425
    Abstract: The migraine-treating effectiveness of a local anesthetic drug is significantly enhanced by coadministering dextromethorphan or dextrorphan.
    Type: Grant
    Filed: May 19, 1997
    Date of Patent: August 17, 1999
    Assignee: Algos Pharmaceutical Corporation
    Inventor: Frank S. Caruso
  • Method of alleviating pain
    Patent number: 5919826
    Abstract: The analgesic effectiveness of an tramadol is significantly enhanced by administering tramadol with the administration of an analgesia-enhancer which is a nontoxic NMDA receptor blocker and/or a nontoxic substance that blocks at least one major intracellular consequence of NMDA receptor activation.
    Type: Grant
    Filed: August 1, 1997
    Date of Patent: July 6, 1999
    Assignee: Algos Pharmaceutical Corporation
    Inventor: Frank S. Caruso
  • Method for treating migraine
    Patent number: 5891885
    Abstract: The migraine-treating effectiveness of an antimigraine drug is significantly enhanced by administering a selective 5-HT.sub.1 agonist together with dextromethorphan or dextrorphan.
    Type: Grant
    Filed: October 24, 1996
    Date of Patent: April 6, 1999
    Assignee: Algos Pharmaceutical Corporation
    Inventor: Frank S. Caruso
  • Wound dressing
    Patent number: 5571079
    Abstract: A wound dressing possessing a wound exudate-absorbing component and at least one liquid-impermeable dressing-securing component is manufactured from the same flexible, cellular, thermoplastic resin workpiece.
    Type: Grant
    Filed: December 30, 1994
    Date of Patent: November 5, 1996
    Assignee: Algos Pharmaceutical Corporation
    Inventors: Gastone P. Bello, John W. Lyle, Donald A. Johnson
  • Transdermal drug delivery device and method for its manufacture
    Patent number: 5505958
    Abstract: A transdermal drug delivery device possessing a drug-storing matrix and at least one drug delivery device-securing component is manufactured from the same flexible cellular thermoplastic resin workpiece.
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: April 9, 1996
    Assignee: Algos Pharmaceutical Corporation
    Inventors: Gastone P. Bello, John W. Lyle, Donald A. Johnson