Abstract: An analyte detection system includes a substrate, a nanowire positioned on the substrate, the nanowire configured to bind with an analyte and a fluorophore, an excitation radiation source configured to irradiate the nanowire with excitation radiation, and a radiation detection device configured to collect radiation emitted by the fluorophore and output from the free end of the nanowire. The substrate may be a reflective substrate, a numerical aperture (NA) of the excitation radiation source may be 0.25 or less, and/or the nanowire may have a diameter D=M*?/[Re(n(?))], wherein 5.5?M?6.5, ? is a peak wavelength of the excitation radiation or a peak wavelength of the collected radiation, and Re(n(?)) is a real part of a refractive index of the nanowire at peak wavelength ?.

Abstract: A gas phase nanowire growth apparatus including a reaction chamber, a first input and a second input. The first input is located concentrically within the second input and the first and second input are configured such that a second fluid delivered from the second input provides a sheath between a first fluid delivered from the first input and a wall of the reaction chamber.

Abstract: A method for transferring an assembly of oriented nanowires from a fluid to a substrate surface, comprising: providing (FIG. 2A) a fluid to a container, said fluid comprising a first liquid (11), a second liquid (12) and a plurality of nanowires (25), wherein the first and second liquids phase separate into a sub phase, a top phase, and an interface (13) between the sub phase and the top phase; wherein the nanowires are functionalized to align vertically into a nanowire aggregate at the interface; wherein the fluid is provided with a substance in a composition configured to change the composition of the top phase or the composition of the sub phase to counteract bulging of the interface (FIG. 2B); and bringing the nanowire aggregate into contact with a substrate surface such that a majority of the nanowires are aligned with respect to each other on the substrate.

Abstract: A nanowire molecular sensor, and a molecular detection system, comprising a nanowire waveguide (30), a nanowire sidewall (51) functionalized in order to attach a molecule (54), and light emissive point sources (52), wherein the amount of light emitted at an end (53) of the waveguide is dependent of the amount of specific molecules attached to the sidewall of the nanowire. A method employing said sensor may be used for single cell detection and analysis.

Abstract: A method for transferring an assembly of oriented nanowires from a fluid to a substrate surface, comprising: providing (FIG. 2A) a fluid to a container, said fluid comprising a first liquid (11), a second liquid (12) and a plurality of nanowires (25), wherein the first and second liquids phase separate into a sub phase, a top phase, and an interface (13) between the sub phase and the top phase; wherein the nanowires are functionalized to align vertically into a nanowire aggregate at the interface; wherein the fluid is provided with a substance in a composition configured to change the composition of the top phase or the composition of the sub phase to counteract bulging of the interface (FIG. 2B); and bringing the nanowire aggregate into contact with a substrate surface such that a majority of the nanowires are aligned with respect to each other on the substrate.

Abstract: A gas phase nanowire growth apparatus including a reaction chamber, a first input and a second input. The first input is located concentrically within the second input and the first and second input are configured such that a second fluid delivered from the second input provides a sheath between a first fluid delivered from the first input and a wall of the reaction chamber.