Patents Assigned to ALK A/S
  • Two-site immunoassay for an antibody with chemiluminescent label and biotin bound ligand
    Patent number: 6087188
    Abstract: A method of detecting an antibody in a sample using a labelling compound and comprising the steps of mixing a ligand antigen, antibody or hapten bound to biotin with the sample; an antibody directed against the antibody to be detected bound to paramagnetic particles; and a chemiluminescent acridinium compound bound to avidin or streptavidin to form a solid phase complex; separating the solid phase from the liquid phase; and analyzing the separated solid phase for the presence of chemiluminescent complex.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: July 11, 2000
    Assignee: ALK A/S
    Inventors: Niels Johansen, Hans-Henrik Ipsen