Patents Assigned to Alkermas Controlled Therapeutics Inc. II
  • Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
    Patent number: 6803055
    Abstract: Sustained-release microparticle composition. The microparticle composition can be formulated to provide multi-phasic release. In one aspect, the composition includes microparticles having more than one rate of release. In another aspect, the composition includes microparticles that exhibit diffusional release and microparticles that exhibit biodegradation release.
    Type: Grant
    Filed: February 6, 2003
    Date of Patent: October 12, 2004
    Assignees: Alkermas Controlled Therapeutics Inc. II, Janssen Pharmaceutica
    Inventors: Jean Mesens, Michael E. Rickey, Thomas J. Atkins
  • Apparatus and method for preparing microparticles
    Patent number: 6713090
    Abstract: Apparatus and method for preparing microparticles. An emulsion is formed by combining two phases in a static mixing assembly. The static mixing assembly preferably includes a preblending static mixer and a manifold. The emulsion flows out of the static mixing assembly into a quench liquid whereby droplets of the emulsion form microparticles. The residence time of the emulsion in the static mixing assembly is controlled to obtain a predetermined particle size distribution of the resulting microparticles.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: March 30, 2004
    Assignee: Alkermas Controlled Therapeutics Inc. II
    Inventors: Shawn L. Lyons, Steven G. Wright