Abstract: Analogs of glucagon-like peptide 2, a product of glucagon gene expression, have been identified as intestinal tissue growth factors. Their formulation as pharmaceutical, and therapeutic use in treating disorders of the small bowel, are described.
Type:
Grant
Filed:
June 28, 1996
Date of Patent:
August 4, 1998
Assignees:
Allelix Biopharmaceutical Inc., 1149336 Ontario Inc.
Inventors:
Daniel J. Drucker, Anna E. Crivici, Martin Sumner-Smith
Abstract: Described herein are isolated polynucleotides which code for an AMPA-type human CNS receptor, designated the human GluR1B receptor. The receptor is characterized structurally and the construction and use of cell lines expressing the receptor is disclosed.
Type:
Grant
Filed:
June 6, 1994
Date of Patent:
March 11, 1997
Assignee:
Allelix Biopharmaceutical Inc.
Inventors:
Rajender Kamboj, Candace E. Elliott, Stephen L. Nutt
Abstract: A novel steroid-binding variant of human corticosteroid binding globulin in which one or more of the glycosylation sites, other than the glycosylation site at amino acid position 238, has been functionally disrupted is complexed with an anti-inflammatory ligand in the treatment of inflammation in mammals.
Type:
Grant
Filed:
April 14, 1995
Date of Patent:
January 21, 1997
Assignee:
Allelix Biopharmaceutical Inc.
Inventors:
Geoffrey L. Hammond, George V. Avvakumov