Abstract: A method for controlling proteolytic action in manufacturing enzyme-treated natural rubber latex and products made therefrom. The method involves adding a protease inhibitor such that hydrolysis by protease enzymes is stopped. A preferred inhibitor is a low molecular weight, cationic protease inhibitor from Fagopyrum esculentum having stability in the pH range of 2–12.
Type:
Grant
Filed:
December 14, 2004
Date of Patent:
December 19, 2006
Assignees:
Roche Diagnostics Operations, Inc., Allergen Reduction, Inc.
Abstract: Disclosed is a method of treating natural rubber latex with protease and peptidase enzymes whereby protein allergens contained within the latex are degraded so as to be rendered non-allergenic to humans. The protein allergen-free natural rubber latex produced by the method and articles fabricated from the protein allergen-free product are also disclosed.