Abstract: The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or treating metastasis in a subject diagnosed with cancer, wherein the method comprises administering to the subject in need thereof an effective amount of a pharmaceutical formulation comprising at least one pharmaceutically acceptable carrier and at least one CX3CR1 or fractalkine antagonist.
Type:
Grant
Filed:
November 22, 2017
Date of Patent:
September 17, 2019
Assignees:
Drexel University, Alliance Discovery, Inc.
Inventors:
Alessandro Fatatis, Joseph M. Salvino, Olimpia Meucci, Whitney L. Gladney
Abstract: The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or treating metastasis in a subject diagnosed with cancer, wherein the method comprises administering to the subject in need thereof an effective amount of a pharmaceutical formulation comprising at least one pharmaceutically acceptable carrier and at least one CX3CR1 or fractalkine antagonist.
Type:
Grant
Filed:
June 6, 2016
Date of Patent:
January 2, 2018
Assignees:
Drexel University, Alliance Discovery, Inc.
Inventors:
Alessandro Fatatis, Joseph M. Salvino, Olimpia Meucci, Whitney L. Gladney
Abstract: The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or treating metastasis in a subject diagnosed with cancer, wherein the method comprises administering to the subject in need thereof an effective amount of a pharmaceutical formulation comprising at least one pharmaceutically acceptable carrier and at least one CX3CR1 or fractalkine antagonist.
Type:
Grant
Filed:
February 25, 2013
Date of Patent:
June 28, 2016
Assignees:
Drexel University, Alliance Discovery, Inc.
Inventors:
Alessandro Fatatis, Joseph M. Salvino, Olimpia Meucci, Whitney L. Gladney
Abstract: The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or treating metastasis in a subject diagnosed with cancer, wherein the method comprises administering to the subject in need thereof an effective amount of a pharmaceutical formulation comprising at least one pharmaceutically acceptable carrier and at least one CX3CR1 or fractalkine antagonist.
Type:
Application
Filed:
February 25, 2013
Publication date:
June 20, 2013
Applicants:
Alliance Discovery, Inc., Philadelphia Health & Education Corporation d/b/a Drexel University College of Medicine
Inventors:
Philadelphia Health & Education Corporation d/b/a Drexel University College of Medicine, Alliance Discovery, Inc.
Abstract: The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or treating metastasis in a subject diagnosed with cancer, wherein the method comprises administering to the subject in need thereof an effective amount of a pharmaceutical formulation comprising at least one pharmaceutically acceptable carrier and at least one CX3CR1 or fractalkine antagonist.
Type:
Grant
Filed:
December 6, 2011
Date of Patent:
May 7, 2013
Assignees:
Philadelphia Health and Education Corporation, Alliance Discovery, Inc.
Inventors:
Alessandro Fatatis, Joseph M. Salvino, Olimpia Meucci, Whitney L. Jamieson