Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

Abstract: A method of reducing or preventing the transfer of pathogens between individuals interacting on artificial turf comprises treating the various components of the artificial turf with a residual antimicrobial coating composition. Treating the artificial turf comprises moving an artificial turf treatment apparatus over the turf in at least one pass, the apparatus being capable of liberating particles of infill material out from between the plastic blades of grass of the artificial turf and spraying the particles with the residual antimicrobial coating composition while the particles are in the air above the turf.

Abstract: A wet wipe is disclosed that provides both contact sanitization of a surface and application of a residual antimicrobial coating on the surface through the same wiping. The wet wipe comprises a substrate such as an absorbent nonwoven fabric and a liquid composition impregnated therein, the liquid composition comprising an organosilane such as the antimicrobial dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride, a non-silane quaternary disinfectant, an organic amine, and a solvent. The non-silane quaternary actives comprise a mixture of actives, and the solvent comprises 60 wt. % isopropanol or more.

Abstract: A method for controlling infections in a facility such as a hospital or foodservice establishment is provided. The method comprises tagging assets, monitoring asset location and pathogen contamination for each asset over time, analyzing data sets to identify which assets are the critical control points for pathogen transfer, and coating a residual self-sanitizing coating composition on each asset identified as a critical control point. The infection control method shuts down pathogen transfer routes by mitigating or eliminating pathogen growth on the critical control points.

Abstract: The present disclosure provides antimicrobial coating compositions that are used to form residual antimicrobial coatings on medical implements and medical devices including the components of medical equipment such as CPAP/BiPAP machines. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an ?-hydroxy acid, a ?-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent, and R9, R10 and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: Antimicrobial coating compositions are used to form dried residual antimicrobial coatings on medical dressings including gauze, bandages, gowns, and dry wipers. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an ?-hydroxy acid, a ?-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.

Abstract: The present disclosure provides antimicrobial coating compositions that are used to form residual antimicrobial coatings on medical implements and medical devices including the components of medical equipment such as CPAP/BiPAP machines. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an ?-hydroxy acid, ?-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent, and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.

Abstract: Antimicrobial coating compositions are used to form dried residual antimicrobial coatings on medical dressings including gauze, bandages, gowns and dry wipers. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N a titanium (IV) species, a 1,2-diol, an ?-hydroxy acid, a ?-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

Abstract: The present disclosure provides antimicrobial coatings on a surface comprising a reactive silanol and triethanolamine. In various examples the reactive silane is 3-chloropropylsilane triol. The coating is capable of reducing the number of Murine norovirus and E. Coli inoculated on the dried coating. In various examples, the coating further comprises a mixture of peroxotitanium acid and peroxo-modified anatase sol. The compositions may be electrostatically sprayed on the surface, and in certain examples, a mixture of silanol and triethanolamine is spray-coated on the surface followed by an aqueous mixture of peroxotitanium acid and peroxo-modified anatase sol.

Abstract: An apparatus is provided for controlling hospital acquired infections by targeting critical control points for pathogen transfer. An infection control apparatus comprises an asset tagging unit; a spraying unit; a power supply unit; optionally a DNA/RNA sequencing unit; and a computing unit comprising a non-transitory computer-readable medium encoded with program instructions for controlling the asset tagging unit and the spraying unit to perform a method of infection control in the facility. In general, the apparatus is used to identify which assets are critical control points for pathogen transfer and to treat those assets with a residual self-sanitizing coating.