Abstract: A non-aqueous composition cleaning system and method for a printing press recirculation system. The cleaning system comprises two powdered compositions, each composition being applied individually to the recirculation system in a two-step process. The first composition is prepared by dry blending 15-30% by weight of an alkaline cleaning agent, 15-30% by weight of a detergent salt, 15-30% by weight of an emulsifying/wetting agent, 15-30% by weight of a silicone antifoam and 0-10% by weight of a free-flowing silica additive. The second composition is prepared by dry blending 20-40% by weight of an organic acid and 60-80% by weight of a non-foaming detergent/wetting agent. The method comprises dissolving 10 to 40 grams of the first composition in 45 to 200 milliliters of water for each gallon of fountain solution and pouring the resultant solution into the printing press recirculation system. The resultant mixture is then allowed to recirculate for at least 30 minutes.