Abstract: The invention relates to assays for testing the therapeutic effectiveness of mesenchymal stem cell (MSC) populations by determining the number of GT repeats in the heme oxygenase-1 (HO-1) promoter region of both alleles.
Abstract: The invention relates to assays for testing the therapeutic effectiveness of mesenchymal stromal cell (MSC) populations and methods of treating pathologies with passaged and/or frozen and thawed MSC populations.
Abstract: The invention relates to mesenchymal stromal cells produced by culturing the cells in platelet lysate supplemented media and methods of using these cells to treat neurological and kidney associated disorders.
Abstract: This application describes the detection and diagnosis of kidney pathology including acute kidney injury by the detection of changes in the amounts of biomarkers in the urine of patients. These biomarkers include stromal derived factor (SDF-1 or CXCL12).