Patents Assigned to Allodynic Therapeutics, LLC
  • COMBINATIONS OF OPIOID/TLR4 ANTAGONISTS AND ACETAMINOPHEN FOR USE IN THE TREATMENT OF EMOTIONAL PAIN AND INSOMNIA
    Publication number: 20190216802
    Abstract: Disclosed are compositions for the treatment of emotional pain, physical pain, and insomnia comprising a compound comprising an opioid antagonist that treats pain by blocking Toll-like receptor 4 (TLR4). Examples of opioid antagonist include naltrexone and naloxone, and their use in the treatment, prevention, and reversal of pain.
    Type: Application
    Filed: March 26, 2019
    Publication date: July 18, 2019
    Applicant: Allodynic Therapeutics, LLC
    Inventor: Annette Channa Toledano
  • Combinations of opioid/TLR4 antagonist and acetyl-para-aminophenol (APAP) for use in the treatment of pain
    Patent number: 9707225
    Abstract: Disclosed are compositions for the treatment of pain comprising a first compound and a second compound, the first compound is an opioid antagonist that treats pain by blocking Toll-like receptor 4 (TLR4) and the second compound is acetyl-para-aminophenol (APAP) that enhances the pain treatment effect of the first compound. Examples of opioid antagonist include naltrexone and naloxone, synergistic pharmaceutical compositions thereof, and their use in the treatment, prevention, and reversal of neuropathic and nociceptive pain.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: July 18, 2017
    Assignee: ALLODYNIC THERAPEUTICS, LLC
    Inventor: Annette Channa Toledano
  • Combinations of opiod/TLR4 antagonist and a cyclooxygenase (COX) inhibitor for use in the treatment of pain
    Patent number: 9205081
    Abstract: Disclosed are compositions for treatment of pain comprising a first compound and a second compound, the first compound is an opioid antagonist that treats pain by blocking Toll-like receptor 4 (TLR4) and the second compound is a cyclooxygenase (COX) inhibitor that enhances the pain treatment effect of the first compound. Examples of opioid antagonist include naltrexone and naloxone. Examples of cyclooxygenase inhibitors include ibuprofen, naproxen, meloxicam, diclofenac and meclofenamic acid, synergistic pharmaceutical compositions thereof, and their use in the treatment, prevention, and reversal of neuropathic pain and nociceptive pain with an allodynic component.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: December 8, 2015
    Assignee: Allodynic Therapeutics, LLC
    Inventor: Annette Channa Toledano
  • Combinations of opioid/TLR4 antagonists and acetyl-para-aminophenol (APAP) for use in the treatment of pain
    Patent number: 9095548
    Abstract: Disclosed are compositions for the treatment of pain comprising a first compound and a second compound, the first compound is an opioid antagonist that treats pain by blocking Toll-like receptor 4 (TLR4) and the second compound is acetyl-para-aminophenol (APAP) that enhances the pain treatment effect of the first compound. Examples of opioid antagonist include naltrexone and naloxone, synergistic pharmaceutical compositions thereof, and their use in the treatment, prevention, and reversal of neuropathic and nociceptive pain.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 4, 2015
    Assignee: Allodynic Therapeutics, LLC
    Inventor: Annette Channa Toledano