Abstract: A vehicle composition in the form of a vesicular composition or a particular composition and, optionally, an active agent associated with the vesicle forming components or particles, and folate receptor alpha is used as a delivery system for the transport of components and/or active agents into the cerebrospinal fluid (CSF) and/or brain and/or central nervous system and/or spinal cord. The composition is used for treating of CSF or brain pertaining diseases, disorders or conditions, such as preventing or treating neurological or neurodegenerative diseases, disorders or conditions.
Type:
Grant
Filed:
October 12, 2012
Date of Patent:
April 24, 2018
Assignees:
Georg-August-Universität Göttingen Stiftung Öffenlichen Rechts, Universitätsmedizin, AllOrphan UG