Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
Type:
Grant
Filed:
November 2, 2009
Date of Patent:
October 29, 2013
Assignee:
Allozyne, Inc.
Inventors:
Kenneth H. Grabstein, Aijun Wang, Natalie Winblade Nairn, Thomas James Graddis, Stephen McCraith, Deepshikha Datta
Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
Type:
Grant
Filed:
April 17, 2008
Date of Patent:
November 9, 2010
Assignee:
Allozyne, Inc.
Inventors:
Kenneth H. Grabstein, Aijun Wang, Natalie Winblade Nairn, Thomas James Graddis
Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
Type:
Grant
Filed:
May 2, 2007
Date of Patent:
December 15, 2009
Assignee:
Allozyne, Inc.
Inventors:
Kenneth H. Grabstein, Andrea Wang, Natalie Winblade Nairn, Stephen McCraith, Deepshikha Datta
Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
Type:
Application
Filed:
August 20, 2007
Publication date:
April 24, 2008
Applicant:
Allozyne, Inc.
Inventors:
Kenneth Grabstein, Aijun Wang, Natalie Nairn, Thomas Graddis