Patents Assigned to Allozyne, Inc.
  • Amino acid substituted molecules
    Patent number: 10407482
    Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: September 10, 2019
    Assignee: ALLOZYNE, INC.
    Inventors: Kenneth H. Grabstein, David A. Tirrell
  • AMINO ACID SUBSTITUTED MOLECULES
    Publication number: 20140255345
    Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
    Type: Application
    Filed: October 16, 2013
    Publication date: September 11, 2014
    Applicant: Allozyne, Inc.
    Inventors: Kenneth H. Grabstein, David A. Tirrell
  • Modified human interferon-beta polypeptides
    Patent number: 8568706
    Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
    Type: Grant
    Filed: November 2, 2009
    Date of Patent: October 29, 2013
    Assignee: Allozyne, Inc.
    Inventors: Kenneth H. Grabstein, Aijun Wang, Natalie Winblade Nairn, Thomas James Graddis, Stephen McCraith, Deepshikha Datta
  • Methods of modifying polypeptides comprising non-natural amino acids
    Patent number: 7829659
    Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: November 9, 2010
    Assignee: Allozyne, Inc.
    Inventors: Kenneth H. Grabstein, Aijun Wang, Natalie Winblade Nairn, Thomas James Graddis
  • AMINO ACID SUBSTITUTED MOLECULES
    Publication number: 20100254943
    Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
    Type: Application
    Filed: November 2, 2009
    Publication date: October 7, 2010
    Applicant: ALLOZYNE, INC.
    Inventors: Kenneth H. Grabstein, Aijun Wang, Natalie Winblade Nairn, Thomas James Graddis, Stephen McCraith, Deepshikha Datta
  • Modified human interferon-? polypeptides
    Patent number: 7632492
    Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
    Type: Grant
    Filed: May 2, 2007
    Date of Patent: December 15, 2009
    Assignee: Allozyne, Inc.
    Inventors: Kenneth H. Grabstein, Andrea Wang, Natalie Winblade Nairn, Stephen McCraith, Deepshikha Datta
  • AMINO ACID SUBSTITUTED MOLECULES
    Publication number: 20080214439
    Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
    Type: Application
    Filed: April 17, 2008
    Publication date: September 4, 2008
    Applicant: ALLOZYNE, INC.
    Inventors: Kenneth H. Grabstein, Aijun Wang, Natalie Winblade Nairn, Thomas James Graddis
  • AMINO ACID SUBSTITUTED MOLECULES
    Publication number: 20080200641
    Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
    Type: Application
    Filed: April 17, 2008
    Publication date: August 21, 2008
    Applicant: ALLOZYNE, INC.
    Inventors: Kenneth H. Grabstein, Aijun Wang, Natalie Winblade Nairn, Thomas James Graddis
  • AMINO ACID SUBSTITUTED MOLECULES
    Publication number: 20080125347
    Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
    Type: Application
    Filed: May 2, 2007
    Publication date: May 29, 2008
    Applicant: ALLOZYNE, INC.
    Inventors: Kenneth H. Grabstein, Aijun Wang, Natalie Winblade Nairn
  • Amino acid substituted molecules
    Publication number: 20080096819
    Abstract: The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
    Type: Application
    Filed: August 20, 2007
    Publication date: April 24, 2008
    Applicant: Allozyne, Inc.
    Inventors: Kenneth Grabstein, Aijun Wang, Natalie Nairn, Thomas Graddis