Abstract: Disclosed are a sonotrode and its use for transdermal delivery of therapeutic or cosmetic compounds. The sonotrode 10 comprises a tubular neck 14 attached at a proximal end to a solid head 12 and ending at a distal end in a flared foot 16. When coupled to an ultrasonic transducer and applied to skin of a human or animal, the sonotrode enhances the delivery of compounds into the skin.

Abstract: Disclosed are methods and devices for processing lipoaspirate that include mechanically-processing harvested lipoaspirate in a liposuction filter canister. In some embodiments, the devices are liposuction devices that include a lipoaspirate processing unit for mechanically-processing lipoaspirate. The mechanical processing reduces the average size of adipose tissue pieces in the lipoaspirate without substantially rupturing lipocytes therein.

Abstract: Disclosed are devices suitable for treatment of subcutaneous tissue by transdermally-inducing ultrasonic vibrations in subcutaneous tissue and/or transdermally delivering energy with electromagnetic radiation such as light to subcutaneous tissue. In some embodiments, the treatment of subcutaneous tissue is effective in reducing the amount of subcutaneous fat therein. In some embodiments, transdermal radiation-delivery of energy and transdermal induction of ultrasonic vibrations in subcutaneous tissue can be performed simultaneously, alternatingly or in an unrelated fashion. In some embodiments, the device simultaneously transdermally-induces both ultrasonic transverse and ultrasonic longitudinal vibrations in subcutaneous tissue.

Abstract: Disclosed are methods and devices for treatment of subcutaneous fat by simultaneously transdermally inducing both ultrasonic transverse vibrations and ultrasonic longitudinal vibrations in subcutaneous tissue, for example for reduction of subcutaneous fat.

Abstract: Disclosed are methods and devices for processing lipoaspirate that include mechanically-processing harvested lipoaspirate in a liposuction filter canister. In some embodiments, the devices are liposuction devices that include a lipoaspirate processing unit for mechanically-processing lipoaspirate. The mechanical processing reduces the average size of adipose tissue pieces in the lipoaspirate without substantially rupturing lipocytes therein.

Abstract: Disclosed are methods for treating a volume of material by concurrently conveying acoustic energy and depositing thermal energy using a unipolar RF (radio-frequency) field. Also disclosed are devices suitable for concurrently conveying acoustic energy and depositing thermal energy using a unipolar RF (radio-frequency) field into the same volume of material. In some embodiments, the disclosed methods and devices are implemented for the treatment of subcutaneous fat.

Abstract: Disclosed are methods for dermatological treatment that in some embodiments include contacting a plurality of cooling probes with an area of skin and maintaining the plurality of cooling probes in contact with the area of skin for a period of time while the distal ends of the plurality of cooling probes substantially cool a volume of tissue, thereby causing a beneficial effect as a result of the substantial cooling of the volume of tissue, as well as devices useful for implementing the method.

Abstract: Methods and apparatus for damaging hair follicles using a series of rapidly-delivered low-fluence pulses of coherent or incoherent light are disclosed herein. In some embodiments, the pulses of coherent or incoherent light have a wavelength or wavelengths primarily in the range between 750 nm and 1500 nm. In some embodiments, applied electromagnetic radiation comprising the rapidly-delivered low-fluence pulses is effective for concomitantly heating both the sub-dermal layer (i.e. the dermis) of the tissue and the hair follicles. In some embodiments, the thermal damaging of the hair follicles is useful for facilitating hair-removal.

Abstract: An apparatus and a method for treating adipose tissue located beneath a patient's skin is disclosed herein. In some embodiments, the apparatus includes a sonotrode 140 and an ultrasound transducer 130 operative to induce longitudinal and/or transversal ultrasound vibrations in a least a portion of the sonotrode 140. In some embodiments, the apparatus provides a “cold” or “transverse” mode where ultrasound energy delivered to the patient is primarily energy of transverse ultrasound waves, and a “hot” or “longitudinal” mode where ultrasound energy delivered to the patient is primarily energy of longitudinal ultrasound waves. The longitudinal waves may be useful for ‘pre-heating’ tissue of the patient before delivering the transverse waves.

Abstract: Disclosed are methods for treating a volume of material by concurrently conveying acoustic energy and depositing thermal energy using a unipolar RF (radio-frequency) field. Also disclosed are devices suitable for concurrently conveying acoustic energy and depositing thermal energy using a unipolar RF (radio-frequency) field into the same volume of material. In some embodiments, the disclosed methods and devices are implemented for the treatment of subcutaneous fat.

Abstract: An apparatus and a method for treating adipose tissue located beneath a patient's skin is disclosed herein. In some embodiments, the apparatus includes a sonotrode and an ultrasound transducer operative to induce longitudinal and/or transversal ultrasound vibrations in a least a portion of the sonotrode. In some embodiments, the apparatus provides a “cold” or “transverse” mode where ultrasound energy delivered to the patient is primarily energy of transverse ultrasound waves, and a “hot” or “longitudinal” mode where ultrasound energy delivered to the patient is primarily energy of longitudinal ultrasound waves. The longitudinal waves may be useful for ‘pre-heating’ tissue of the patient before delivering the transverse waves.

Abstract: A skin treatment device combines an RF treatment arrangement with a mechanical massage arrangement, preferably with the massage device in the form of an annular massage head encircling and rotating around the RF applicator. Also disclosed are configurations with a liquid dispenser for delivering a liquid to the skin under the device. According to one option, the skin contact surface of the RF applicator itself is provided in part by a rolling ball liquid applicator.

Abstract: A system 30 and method(s) 100 for thermal treatment of a selected target within a subject is disclosed. System 30 includes RF source 10, phase shifter 14, impedance matching network 11 and resonator 13. Stationary water molecules 1, such as those in fat cells, are heated. The invention is useful in selective heating of cellulite bodies as a means of treating cellulite.

Abstract: A system 30 and method(s) 100 for thermal treatment of a selected target within a subject is disclosed. System 30 includes RF source 10, phase shifter 14, impedance matching network 11 and resonator 13. Stationary water molecules 1, such as those in fat cells, are heated. The invention is useful in selective heating of cellulite bodies as a means of treating cellulite.

Abstract: A robotic system for delivering energy for medical or cosmetic treatment of a region of skin of a subject includes a multi-axis robotic arm mounted on a base and terminating at a holder. An applicator for delivering energy to the skin is mounted in the holder. The holder has at least three range sensors generating outputs of a distance to at least three spaced apart locations on the surface of the skin. A controller associated with the robotic arm and the range sensors processes the outputs from the at least three range sensors to determine an orientation of the holder relative to the skin, and actuates the robotic arm to adjust an orientation of the holder such that an orientation of the applicator relative to the skin is maintained within a predefined range of desired angles.

Abstract: Disclosed are methods for dermatological treatment that in some embodiments include contacting a plurality of cooling probes with an area of skin and maintaining the plurality of cooling probes in contact with the area of skin for a period of time while the distal ends of the plurality of cooling probes substantially cool a volume of tissue, thereby causing a beneficial effect as a result of the substantial cooling of the volume of tissue, as well as devices useful for implementing the method.

Abstract: An apparatus and a method for treating adipose tissue located beneath a patient's skin is disclosed herein. In some embodiments, the apparatus includes a sonotrode 140 and an ultrasound transducer 130 operative to induce longitudinal and/or transversal ultrasound vibrations in a least a portion of the sonotrode 140. In some embodiments, the apparatus provides a “cold” or “transverse” mode where ultrasound energy delivered to the patient is primarily energy of transverse ultrasound waves, and a “hot” or “longitudinal” mode where ultrasound energy delivered to the patient is primarily energy of longitudinal ultrasound waves. The longitudinal waves may be useful for ‘pre-heating’ tissue of the patient before delivering the transverse waves.

Abstract: A skin treatment device combines an RF treatment arrangement with a mechanical massage arrangement, preferably with the massage device in the form of an annular massage head encircling and rotating around the RF applicator. Also disclosed are configurations with a liquid dispenser for delivering a liquid to the skin under the device. According to one option, the skin contact surface of the RF applicator itself is provided in part by a rolling ball liquid applicator.

Abstract: A system 30 and method(s) 100 for thermal treatment of a selected target within a subject is disclosed. System 30 includes RF source 10, phase shifter 14, impedance matching network 11 and resonator 13. Stationary water molecules 1, such as those in fat cells, are heated. The invention is useful in selective heating of cellulite bodies as a means of treating cellulite.

Abstract: A system 30 and method(s) 100 for thermal treatment of a selected target within a subject is disclosed. System 30 includes RF source 10, phase shifter 14, impedance matching network 11 and resonator 13. Applicator 3 conveys output signal 17 from energy source 10 through surface 6 of biological tissue 4 to predetermined energy dissipation zone 5 after output 17 has been processed by the phase shifter 14, IMN 11 and resonator 13. Stationary water molecules 1, such as those in fat cells, are heated. System 30 is operative to heat a volume of biological tissue beneath the biological tissue surface 6 such that surface 6 of biological tissue 4 is maintained at a lower temperature than predetermined energy dissipation zone 5 without a cooling device. The invention is useful in selective heating of cellulite bodies as a means of treating cellulite.