Patents Assigned to Almirall Prodesfarma S.A.
  • Patent number: 8129405
    Abstract: The invention provides 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide in powder inhalant form, and methods of using it for treatment of respiratory disorders.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: March 6, 2012
    Assignee: Almirall Prodesfarma S.A.
    Inventors: Maria Dolors Fernandez Forner, Maria Prat Quiñones, María Antonia Buil Albero
  • Patent number: 7897617
    Abstract: The invention provides 3-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2] octane in salt form, pharmaceutical compositions comprising it, and methods of using it for treatment of respiratory disorders, in association with steroids.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: March 1, 2011
    Assignee: Almirall Prodesfarma S.A.
    Inventors: Maria Dolors Fernandez Forner, Maria Prat Quiñones, Maria Antonia Buil Albero
  • Patent number: 7189741
    Abstract: The invention relates to indolyl piperidinyl derivatives of formula (I) wherein: A1 represents an alkylene, alkyleneoxy, alkylenethio, alkanoylene or hydroxyalkylene group; A2 represents an alkylene, alkyleneoxy, alkylenethio, alkanoylene or an alkyleneoxyalkylene group; W1 represents a phenylene, furanylene or pyridinylene group which is unsubstituted or substituted by one or more halogen atoms, alkoxy groups and/or alkyl groups; W2 represents a 3–10 membered monocyclic or bicyclic group containing from 1 to 3 heteroatoms said group being unsubstituted or substituted by one or more halogen atoms, alkyl groups, alkoxy groups and/or oxo groups; R1 represents a hydrogen or halogen atom or an alkyl, alkoxy or methylamino group; and R2 represents a carboxyl group; and pharmaceutically acceptable salts thereof; to processes for their preparation; to pharmaceutical compositions containing them; and to their medical use as antihistaminic and antiallergic agents.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: March 13, 2007
    Assignee: Almirall Prodesfarma S.A.
    Inventors: Silvia Fonquerna Pou, Lluis Pages Santacana, Carles Puig Duran, Lidia Soca Pueyo
  • Patent number: 7060824
    Abstract: This invention relates to new therapeutically useful 8-(disubstituted)phenyl-6,9-dihydro-5H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine-5-one and 8-phenyl-6,9-dihydro-5H-pyrrolo[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine-5-one derivatives of formula (I): wherein: —X—C—Y— represents (a) or (b) to processes and intermediates for their preparation, to pharmaceutical compositions containing them and to their medical uses as potent and selective inhibitors of phosphodiesterase 5 (PDE 5).
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: June 13, 2006
    Assignee: Almirall Prodesfarma, S.A.
    Inventors: Bernat Vidal Juan, Cristina Esteve Trias, Jordi Gracia Ferrer, José Manuel Prieto Soto
  • Patent number: 7034016
    Abstract: 8-phenyl-6,9-dihydro-[1,2,4]triazolo[3,4-i]purin-5-one derivatives of formula (I): or a pharmaceutically acceptable salt thereof processes for their preparation, pharmaceutical compositions containing them and their use as PDE 5 inhibitors.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: April 25, 2006
    Assignee: Almirall Prodesfarma, S.A.
    Inventors: Jordi Gracia Ferrer, Joan Feixas Gras, José Manuel Prieto Soto, Armando Vega Noverola, Bernat Vidal Juan
  • Patent number: 6943253
    Abstract: The invention relates to new 6-phenylpyrrolopyrimidine derivatives of formula (I): wherein: —X—C—Y— represents or —X—C—Y— represents and to their use as selective cyclic GMP specific phosphodiesterase (PDE 5)inhibitors, processes for producing them, intermediates used in their production, compositions containing them and their applicability in medical treatment of the human or animal body.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: September 13, 2005
    Assignee: Almirall Prodesfarma S.A.
    Inventors: Bernat Vidal Juan, Jordi Gracia Ferrer, José Manuel Prieto Soto, Armando Vega Noverola
  • Patent number: 6750226
    Abstract: A compound according to formula (I) wherein: is a phenyl ring, a C4 to C9 heteroaromatic compound containing one or more heteroatoms, or a naphthalenyl, 5,6,7,8-tetrahydronaphthalenyl or biphenyl group; which shows high affinity for muscarinic M3 receptors (Hm3).
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: June 15, 2004
    Assignee: Almirall-Prodesfarma, S.A.
    Inventors: Dolors Fernandez Forner, Maria Prat Quiñones, Maria Antonia Buil Albero
  • Patent number: 6683096
    Abstract: Indolylpiperidine compounds of formula (I) wherein: A1 represents an alkylene, alkyleneoxy, alkylenethio, alkanoyl or hydroxyalkylene group; A2 represents a single bond, an alkylene or alkenylene group; W represents a single bond or a phenylene or furanylene group which is unsubstituted or substituted by one or more halogen atoms, alkoxy groups and/or alkyl groups; R2 represents a hydrogen or halogen atom or an alkyl or alkoxy group; and R3 represents a carboxyl group or a tetrazolyl group. The present invention provides novel indolylpiperidine compounds having imporved antihistamine and antiallergic activity.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: January 27, 2004
    Assignee: Almirall Prodesfarma, S.A.
    Inventors: Lluis Pages Santacana, Silvia Fonquerna Pou, Carles Puig Duran, Maria Dolors Fernandez Forner
  • Patent number: 6518303
    Abstract: 2-Phenylpyran-4-one derivatives of formula (I): wherein: R1 represents an alkyl or —NR4R5 group, wherein R4 and R5 each independently represents a hydrogen atom or an alkyl group; R2 represents an alkyl, C3-C7 cycloalkyl, pyridyl, thienyl, naphthyl, tetrahydronaphthyl or indanyl group, or a phenyl group which may be unsubstituted or substituted by one or more halogen atoms or alkyl, trifluoromethyl, hydroxy, alkoxy, methylthio, amino, mono- or dialkylamino, hydroxalkyl or hydroxycarbonyl groups; R3 represents a methyl, hydroxymethyl, alkoxymethyl, C3-C7 cycloalkoxymethyl, benzyloxymethyl, hydroxycarbonyl, nitrile, trifluoromethyl or difluoromethyl group or a CH2—R6 group wherein R6 represents an alkyl group; and X represents a single bond, an oxygen atom, a sulfur atom or a methylene group; or pharmaceutically acceptable salts thereof, processes for their production and synthetic intermediates used in said processes, pharmaceutical compositions containing them and their use
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: February 11, 2003
    Assignee: Almirall Prodesfarma S.A.
    Inventors: Maria Isabel Crespo Crespo, Juan Miguel Jimenez Mayorga, Carles Puig Duran, Lidia Soca Pueyo
  • Publication number: 20020183326
    Abstract: Heterocyclic compounds of formula (I), 1
    Type: Application
    Filed: January 8, 2002
    Publication date: December 5, 2002
    Applicant: ALMIRALL PRODESFARMA, S.A.
    Inventors: Jordi Gracia Ferrer, M. Isabel Crespo Crespo, Armando Vega Noverola, Andres Fernandez Garcia
  • Patent number: 6407108
    Abstract: Heterocyclic compounds of formula(I), wherein R1 represents a hydrogen atom or a —(CH2)m—Y group, wherein m is an integer from 0 to 4 and Y represents an alkyl, haloalkyl, alkoxy, alkoxycarbonyl, C3-C7 cycloalkyl, norbornyl or phenylalkenyl group, or an aromatic group which aromatic group {circumflex over ( )} may optionally be substituted by one or more halogen atoms; R2 represents an aromatic group which aromatic group may optionally be substituted by one or more halogen atoms or alkyl, alkoxy, C3-C6 cycloalkoxy, methylenedioxy, nitro, dialkylamino or trifluoromethyl groups, and R3 represents a hydrogen or halogen atom or an alkyl group, and pharmaceutically acceptable salts thereof, processes for preparing the same are disclosed herein. The compounds are phosphodiesterase 4 inhibitors.
    Type: Grant
    Filed: January 28, 2000
    Date of Patent: June 18, 2002
    Assignee: Almirall Prodesfarma, S.A.
    Inventors: Jordi Gracia Ferrer, Ma Isabel Crespo Crespo, Armando Vega Noverola, Andres Fernandez Garcia