Abstract: Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or in treating cancer, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B, D, E, G and R1-R5 are as defined in the specification, with one or more of D, E and G, preferably E, is hydroxy.
Type:
Application
Filed:
September 19, 2023
Publication date:
January 4, 2024
Applicant:
AlonBio Ltd.
Inventors:
Amnon PELED, Michal ABRAHAM KARNI, Orly EIZENBERG
Abstract: Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or in treating cancer, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B, D, E, G and R1-R5 are as defined in the specification, with one or more of D, E and G, preferably E, is hydroxy.
Type:
Grant
Filed:
January 27, 2022
Date of Patent:
October 10, 2023
Assignee:
AlonBio Ltd.
Inventors:
Amnon Peled, Michal Abraham Karni, Orly Eizenberg
Abstract: Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or in treating cancer, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B, D, E, G and R1-R5 are as defined in the specification, with one or more of D, E and G, preferably E, is hydroxy.
Type:
Grant
Filed:
August 10, 2020
Date of Patent:
March 1, 2022
Assignee:
AlonBio Ltd.
Inventors:
Amnon Peled, Michal Abraham Karni, Orly Eizenberg