Abstract: A composition and method for supplementing feed, nutrition and diet systems with bioactive glycerides of conjugated linoleic acid comprised of a synergistic blend of conjugated linoleic bioactive isomers acid in mono-, di-, and/or triglyceride form. The composition comprises (A) bioactive glycerides of conjugated linoleic acid comprised of a synergistic blend of conjugated linoleic bioactive isomers acid in mono-, di- and/or triglyceride form, (B) a carrier medium, and (C) a delivery system as a dietary supplement. The composition provides an effective increase in nutritional, therapeutic, and pharmacological properties in nutrition and diet systems.