Abstract: The invention relates to bioengineering and medical modular systems for the realization of self-contained equipment for influencing biological media, cells, tissue and tissue-like structures as objects. These modular systems distinguish themselves, in particular, by the fact that the user-specific equipment for influencing the objects can be realized in a simple and economically effective way. A tub-shaped main body for placement of elements that can be combined with one another is provided for this. Furthermore, at least one container for a liquid medium, a pumping system for a liquid medium, connection elements, filters for the inlet and outlet of gas, at least one filter with a connecting element for a medium, elements for a connection to at least one bioreactor, at least one gas inlet unit or a combination of at least one bioreactor and at least one gas inlet unit are components of the modular system.
Abstract: A device for supplying cell culture modules with nutrients has an arrangement of channels, pumps and valves in or on a plate. The valves may be pinch valves operated by deforming an elastic section of a conduit and the pump may be a pinch valve pump. The channels may be defined, at least in part, by the plate. The pumps, channels and valves may be located within the thickness of the plate. The device may be used to supply nutrients to cell culture modules according to a perfusion operation, a re-circulation operation and/or a combination of both.
Type:
Grant
Filed:
May 8, 2006
Date of Patent:
April 5, 2011
Assignee:
ALPHA PLAN GmbH
Inventors:
Uwe Klaus, Rudolph Luning, Laurence J. Purcell, Stefan Doring