Patents Assigned to Alphamed Pharmaceuticals Corp.
  • DNA for expression of alpha 1-antitrypsin in methylotropic yeast
    Patent number: 7270979
    Abstract: Alpha 1-antitrypsin is prepared by growing in a fermentor methylotropic yeast transformants containing in their genome at least one copy of DNA encoding alpha 1-antitrypsin, in operational linkage with DNA encoding a signal sequence, which is effective for directing secretion of proteins from the host cells, DNA constructs and recombinant yeast strains used for the expression and secretion of alpha 1-antritrypsin are also provided. The fermentation medium requires a pH of 6.5 to 7.5. The fermentation is at a pH between 5 and 6.8.
    Type: Grant
    Filed: September 26, 2003
    Date of Patent: September 18, 2007
    Assignee: Alphamed Pharmaceuticals Corp
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Topical wound therapeutic compositions
    Patent number: 6573249
    Abstract: There is provided a composition for healing burns and wounds in mammals, which contains a cromolyn compound or the combination of a cromolyn compound and hyaluronic acid a corticosteroid. Advantageously, elements found in amniotic fluid are also included.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: June 3, 2003
    Assignee: AlphaMed Pharmaceutical Corp.
    Inventors: John Lezdey, Darren Lezdey
  • Treatment of collagen related diseases
    Patent number: 6566331
    Abstract: The present invention provides for the treatment of a patient suffering from a collagen related disease utilizing a serine protease inhibitor. The treatment includes the use of a corticosteroid that is administered separately or in combination. The serine proteases preferred are alpha 1-antitrypsin, alpha 2-macroglobulin and secretory leucocyte protease inhibitor.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: May 20, 2003
    Assignee: Alphamed Pharmaceutical Corp
    Inventors: Darren Lezdey, K. Anne Kronis, John Lezdey
  • Treatment of lupus erythematosus
    Patent number: 6537968
    Abstract: The present invention provides for the treatment of an individual suffering from lupus erythematosus utilizing a serine protease inhibitor. The treatment includes the use of a corticosteroid that is administered separately or in combination. The serine proteases preferred are alpha 1-antitrypsin, secretory leucocyte protease inhibitor, alpha 2-macroglobulin or mixtures thereof.
    Type: Grant
    Filed: July 24, 2000
    Date of Patent: March 25, 2003
    Assignee: Alphamed Pharmaceuticals Corp
    Inventors: Darren Lezdey, Jarett Lezdey
  • Cromolyn for eye and ear infections
    Patent number: 6511960
    Abstract: The present invention provides a method and composition for treating eye and ear inflammation and eye and ear infections. The compositions contain a cromolyn compound alone or in combination with a corticosteroid. A steroidal antiphlogistic compound, a non-steroidal antiphlogistic compound and optionally hyaluronic acid may be added.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: January 28, 2003
    Assignee: Alphamed Pharmaceuticals Corp
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Method for treating infectious viral diseases
    Patent number: 6468557
    Abstract: The present invention provides for the treatment of an individual suffering from infections from herpes virus or human papilloma virus by utilizing a cromolyn compound. The treatment includes the use of a corticosteroid or L-lysine that can be administered separately or in combination.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: October 22, 2002
    Assignee: AlphaMed Pharmaceutical Corp.
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Topical wound therapeutic compositions
    Patent number: 6262020
    Abstract: There is provided a composition for healing burns and wounds in mammals which contains the combination of hyaluronic acid and a serine protease inhibitor. Advantageously, elements found in amniotic fluid are also included.
    Type: Grant
    Filed: February 15, 2000
    Date of Patent: July 17, 2001
    Assignee: Alphamed Pharmaceuticals Corp.
    Inventors: John Lezdey, Darren B. Lezdey