Patents Assigned to Alpharma AS
  • Cytotoxic modified lactoferrin peptides
    Patent number: 6890902
    Abstract: The present invention provides a modified lactoferrin peptide which is cytotoxic, 7 to 25 amino acids in length, with three or more cationic residues and which has one or more extra bulky and lipophilic amino acids as compared to the native lactoferrin sequence, as well as esters, amides, salts and cyclic derivatives thereof as well as methods of preparing such peptides, pharmaceutical compositions containing such peptides and use of the peptides as medicaments, particularly as antibacterials or anti-tumoural agents.
    Type: Grant
    Filed: February 27, 2001
    Date of Patent: May 10, 2005
    Assignee: Alpharma AS
    Inventors: John Sigurd Svendsen, Oystein Rekdal, Baldur Sveinbjornsson, Lars Vorland
  • Bioactive peptides
    Publication number: 20030022821
    Abstract: The present invention provides a modified lactoferrin peptide which is cytotoxic, 7 to 25 amino acids in length, with three or more cationic residues and which has one or more extra bulky and lipophilic amino acids as compared to the native lactoferrin sequence, as well as esters, amides, salts and cyclic derivatives thereof as well as methods of preparing such peptides, pharmaceutical compositions containing such peptides and use of the peptides as medicaments, particularly as antibacterials or anti-tumoural agents.
    Type: Application
    Filed: February 27, 2001
    Publication date: January 30, 2003
    Applicant: ALPHARMA AS
    Inventors: John Sigurd Svenden, Oystein Rekdal, Baldur Sveinbjornsson, Lars Vorland