Abstract: An aqueous pharmaceutical composition suitable for oral delivery has an insoluble active substance and a wetting agent in liquid suspension. The composition contains floccules of the active ingredient. The formulation has an excellent shelf-life in which caking and sedimentation are inhibited. The composition may be resuspended upon light to moderate shaking.
Type:
Grant
Filed:
July 21, 2000
Date of Patent:
December 2, 2003
Assignee:
Alpharma USPD Inc.
Inventors:
Subhas Kundu, Vivek Desai, Andrea Cameron
Abstract: A stable aqueous suspension including a substantially water-insoluble drug suspended in a completely water-soluble mixture including hydroxypropylmethylcellulose, polyoxyethylene sorbitan monooleate, and xanthan gum.