Patents Assigned to ALS Therapy Development Foundation
  • Treatment of neurodegenerative diseases using proteasome modulators
    Publication number: 20040138153
    Abstract: Methods for modulating proteasome activity in a subject is provided. Proteasome activity is modulated by administering a therapeutically effective amount of proteasome modulating pharmacological agent to a subject. In a preferred embodiment, the proteasome modulating pharmacological agent is a protease inhibitor. In another aspect, a screening assay for detecting and identifying proteasome modulating pharmacological agents to modulate proteasome activity in a subject is also provided.
    Type: Application
    Filed: June 3, 2003
    Publication date: July 15, 2004
    Applicant: ALS Therapy Development Foundation
    Inventors: Tennore Ramesh, Sean Scott