Patents Assigned to ALSaTECH, Inc.
  • Method of solubilizing TDP-43 protein aggregates in amyotrophic lateral sclerosis using a microvascular endothelial cell expressing an anti-TDP-43 Fab
    Patent number: 12016885
    Abstract: The present invention relates, in part, to cell-based gene therapies, including those targeting, by way of non-limiting example, TDP43 and A? aggregates, for the use in neurodegenerative disorders, including without limitation Amyotrophic Lateral Sclerosis (ALS) and Alzheimer's Disease, respectively.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: June 25, 2024
    Assignee: ALSaTECH, Inc.
    Inventors: Claude Nicolau, Claudine Kieda, Reynald Thinard, Ruth Greferath, Melanie Chevalier
  • Microvascular endothelial cell comprising a nucleic acid encoding an anti-TDP-43 fab
    Patent number: 12016886
    Abstract: The present invention relates, in part, to cell-based gene therapies, including those targeting, by way of non-limiting example, TDP43 and A? aggregates, for the use in neurodegenerative disorders, including without limitation Amyotrophic Lateral Sclerosis (ALS) and Alzheimer's Disease, respectively.
    Type: Grant
    Filed: October 14, 2022
    Date of Patent: June 25, 2024
    Assignee: ALSaTECH, Inc.
    Inventors: Claude Nicolau, Claudine Kieda, Reynald Thinard, Ruth Greferath, Melanie Chevalier