Patents Assigned to ALSGEN, LLC
  • Small interference RNA (siRNA) molecules for modulating superoxide dismutase (SOD)
    Publication number: 20060229268
    Abstract: The invention pertains to using double stranded ribonucleic acid molecules such as small interfering RNA (siRNA) molecules to target an SOD gene to interfere with gene expression and SOD protein production. Method are disclosed for inhibiting expression of a target protein in a subject with a neurological disorder by introducing a small interference ribonucleic acid (siRNA) molecule into the subject with the neurological disorder, such as amyotrophic lateral sclerosis (ALS).
    Type: Application
    Filed: December 16, 2005
    Publication date: October 12, 2006
    Applicant: ALSGEN, LLC
    Inventors: Daniel Benjamin, Sean Scott
  • Modulation of neurodegenerative diseases through the estrogen receptor
    Publication number: 20060211673
    Abstract: Methods for modulating hormonal pathways involving the estrogen receptor in a subject with a neurodegenerative disorder, are provided. Estrogen receptor activity is modulated by administering an effective amount of an estrogen receptor modulating pharmacological agent to a subject such that the estrogen receptor modulating pharmacological agent interacts with the estrogen receptor and alters the expression of a protein associated with the neurodegenerative disease.
    Type: Application
    Filed: March 1, 2006
    Publication date: September 21, 2006
    Applicant: ALSGEN, LLC
    Inventors: Sean Scott, Daniel Benjamin
  • Modulation of neurodegenerative diseases
    Publication number: 20060211645
    Abstract: Methods and compositions are disclosed for selectively interfering with protein synthesis in a central nervous system, meningial, or muscle cell by administrating a pharmacological agent. In particular, methods and compositions that interfere with SOD-1 protein synthesis are disclosed.
    Type: Application
    Filed: March 1, 2006
    Publication date: September 21, 2006
    Applicant: ALSGEN, LLC
    Inventors: Sean Scott, Daniel Benjamin
  • Modulation of neurodegenerative diseases through the progesterone receptor
    Publication number: 20060205704
    Abstract: Methods for modulating hormonal pathways involving the progesterone receptor in a subject with a neurodegenerative disorder, are provided. Progesterone receptor activity is modulated by administering an effective amount of an progesterone receptor modulating pharmacological agent to a subject such that the progesterone receptor modulating pharmacological agent interacts with the progesterone receptor and alters the expression of a protein associated with the neurodegenerative disease.
    Type: Application
    Filed: March 1, 2006
    Publication date: September 14, 2006
    Applicant: ALSGEN, LLC
    Inventors: Sean Scott, Daniel Benjamin