Abstract: A fluticasone lotion having improved vasoconstrictor and anti-inflammatory activity and higher than expected potency. The fluticasone lotion contains 0.05 weight percent fluticasone propionate and an oil-in-water vehicle that includes excipients. The fluticasone lotion is unexpectedly efficacious while exhibiting an improved safety profile.
Type:
Grant
Filed:
March 15, 2004
Date of Patent:
November 27, 2007
Assignee:
Altana Inc.
Inventors:
Gordon J. Dow, Keith Arthur Johnson, Frances Furr Kelly, Robert William Lathrop, Rukmini Rajagopalan