Patents Assigned to AltraVax, Inc.
  • Hepatitis B virus vaccines
    Patent number: 9353158
    Abstract: This document provides methods and materials for producing immune responses against hepatitis B viruses. For example, polypeptides, nucleic acid molecules encoding such polypeptides, virus-like particles containing such polypeptides, vaccine preparations containing one or more polypeptides provided herein, vaccine preparations containing one or more nucleic acid molecules provided herein, vaccine preparations containing one or more virus-like particles provided herein, and methods for inducing immune responses against hepatitis B viruses within mammals (e.g., humans) are provided.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: May 31, 2016
    Assignee: Altravax, Inc.
    Inventors: Robert Gerald Whalen, Clayton W. Beard, Li Xu, Hakima Sbai
  • Recombinant dengue virus antigen comprising the capsid protein leader sequence, full-length prM protein, and full-length E protein
    Patent number: 9186397
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: November 17, 2015
    Assignee: Altravax, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • RECOMBINANT DENGUE VIRUS ANTIGEN COMPRISING THE CAPSID PROTEIN LEADER SEQUENCE, FULL-LENGTH prM PROTEIN, AND FULL-LENGTH E PROTEIN.
    Publication number: 20150290313
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Application
    Filed: March 11, 2014
    Publication date: October 15, 2015
    Applicant: Altravax, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • Recombinant dengue virus antigen comprising the capsid protein leader sequence, full-length prM protein, and full-length E protein
    Patent number: 8715694
    Abstract: The invention provides polypeptides and virus-like particles having, for example, an ability to induce an immune response to flaviviruses. The polypeptides can include C15, prM, and E polypeptide sequences.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: May 6, 2014
    Assignee: Altravax, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • Nucleic acids encoding novel chimeric C15/prM/E dengue virus immunogens prepared by DNA shuffling
    Patent number: 8168772
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: May 1, 2012
    Assignee: Altravax, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman
  • Recombinant dengue virus antigens comprising the C15 signal peptide, full-length PRM protein, and full-length E protein
    Patent number: 8158131
    Abstract: The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: April 17, 2012
    Assignee: AltraVax, Inc.
    Inventors: Doris Apt, Juha Punnonen, Alice M. Brinkman