Patents Assigned to Amaranth Medical Pte.
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Patent number: 10646359Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: GrantFiled: May 21, 2012Date of Patent: May 12, 2020Assignee: Amaranth Medical Pte.Inventors: Kamal Ramzipoor, Alfred N. K. Chia, Liwei Wang
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Patent number: 9908143Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: GrantFiled: May 21, 2012Date of Patent: March 6, 2018Assignee: Amaranth Medical Pte.Inventors: Kamal Ramzipoor, Alfred N. K. Chia, Liwei Wang, Chang Y. Lee
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Publication number: 20170246243Abstract: Bioresorbable scaffolds for treatment of bifurcation lesion are described herein. Generally, an expandable scaffold may be fabricated from a high molecular weight isotropic PLLA material, wherein the scaffold incorporates one or more strain relief features which are configured to allow side branch treatment.Type: ApplicationFiled: February 6, 2017Publication date: August 31, 2017Applicant: Amaranth Medical Pte.Inventors: Kamal RAMZIPOOR, Chang Y. LEE
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Publication number: 20170157806Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: ApplicationFiled: February 22, 2017Publication date: June 8, 2017Applicant: Amaranth Medical Pte.Inventors: Kamal RAMZIPOOR, Alfred N. K. CHIA, Liwei WANG
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Publication number: 20150342764Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: ApplicationFiled: May 18, 2015Publication date: December 3, 2015Applicant: Amaranth Medical Pte.Inventors: Kamal RAMZIPOOR, Chang Y. LEE
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Publication number: 20150051686Abstract: Bioresorbable scaffolds for treatment of bifurcation lesion are described herein. Generally, an expandable scaffold may be fabricated from a high molecular weight isotropic PLLA material, wherein the scaffold incorporates one or more strain relief features which are configured to allow side branch treatment.Type: ApplicationFiled: July 17, 2014Publication date: February 19, 2015Applicant: Amaranth Medical Pte.Inventors: Kamal RAMZIPOOR, Chang Y. LEE
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Publication number: 20140330359Abstract: For scaffolds delivered and deployed intravascularly, one or several configurations may be employed for creating a smoother transition from balloon-to-scaffold. For instance, one or more spacers may be positioned in proximity to the scaffold. Alternatively, portions of the inflatable balloon may be configured to provide a smooth transition. In another alternative, the stent edges may be shaped to provide a smooth transition. In yet other variations, any number of different combinations of such features may be employed.Type: ApplicationFiled: April 14, 2014Publication date: November 6, 2014Applicant: AMARANTH MEDICAL PTE.Inventors: Kamal RAMZIPOOR, Chang Y. LEE, Edward A. ESTRADA
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Patent number: 8858611Abstract: Sterilization methods for implantable prostheses are described where a polymeric stent may be sterilized, e.g., via ETO sterilization, at a temperature below a glass transition temperature of the stent. A separate delivery catheter may be sterilized separately and the stent and delivery catheter may then be combined in an aseptic or semi-aseptic environment and sterilized as an assembled system such that the requirements for sterilizing the system are relatively lower. Additionally and/or alternatively, valve and filter assemblies may be used with an optional mandrel assembly for maintaining sterility of the internal components of a catheter system.Type: GrantFiled: July 3, 2013Date of Patent: October 14, 2014Assignee: Amaranth Medical, PteInventors: Kamal Ramzipoor, Chang Y. Lee, Fozan O. El-Nounou
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Publication number: 20140236285Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: ApplicationFiled: April 23, 2014Publication date: August 21, 2014Applicant: AMARANTH MEDICAL PTE.Inventors: Kamal RAMZIPOOR, Alfred N. K. CHIA, Liwei WANG
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Publication number: 20140039600Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: ApplicationFiled: September 18, 2013Publication date: February 6, 2014Applicant: AMARANTH MEDICAL PTE.Inventors: Kamal RAMZIPOOR, Alfred N. K. CHIA, Liwei WANG
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Publication number: 20140035192Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: ApplicationFiled: September 18, 2013Publication date: February 6, 2014Applicant: AMARANTH MEDICAL PTE.Inventors: Kamal RAMZIPOOR, Alfred N. K. CHIA, Liwei WANG
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Patent number: 8574493Abstract: Sterilization methods for implantable prostheses are described, where a polymeric stent may be sterilized, e.g., via ETO sterilization, at a temperature below a glass transition temperature of the stent. A separate delivery catheter may be sterilized separately and the stent and delivery catheter may then be combined in an aseptic, or semi-aseptic environment and sterilized as an assembled system such that the requirements for sterilizing the system are relatively lower. Additionally and/or alternatively, valve and filter assemblies may be used with an optional mandrel assembly for maintaining sterility of the internal components of a catheter system.Type: GrantFiled: November 7, 2012Date of Patent: November 5, 2013Assignee: Amaranth Medical Pte.Inventors: Kamal Ramzipoor, Chang Y. Lee, Fozan O. El-Nounou
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Publication number: 20130138197Abstract: Sterilization methods for implantable prostheses are described, where a polymeric stent may be sterilized, e.g., via ETO sterilization, at a temperature below a glass transition temperature of the stent. A separate delivery catheter may be sterilized separately and the stent and delivery catheter may then be combined in an aseptic, or semi-aseptic environment and sterilized as an assembled system such that the requirements for sterilizing the system are relatively lower. Additionally and/or alternatively, valve and filter assemblies may be used with an optional mandrel assembly for maintaining sterility of the internal components of a catheter system.Type: ApplicationFiled: November 7, 2012Publication date: May 30, 2013Applicant: AMARANTH MEDICAL PTE.Inventor: Amaranth Medical Pte.
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Patent number: 8309023Abstract: Sterilization methods for implantable prostheses are described where a polymeric stent may be sterilized, e.g., via ETO sterilization, at a temperature below a glass transition temperature of the stent. A separate delivery catheter may be sterilized separately and the stent and delivery catheter may then be combined in an aseptic or semi-aseptic environment and sterilized as an assembled system such that the requirements for sterilizing the system are relatively lower. Additionally and/or alternatively, valve and filter assemblies may be used with an optional mandrel assembly for maintaining sterility of the internal components of a catheter system.Type: GrantFiled: December 29, 2009Date of Patent: November 13, 2012Assignee: Amaranth Medical Pte.Inventors: Kamal Ramzipoor, Chang Y. Lee, Fozan O. El-Nounou
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Publication number: 20120232643Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: ApplicationFiled: May 21, 2012Publication date: September 13, 2012Applicant: AMARANTH MEDICAL PTE.Inventors: Kamal RAMZIPOOR, Alfred N. K. CHIA, Liwei WANG
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Patent number: 8206636Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: GrantFiled: June 19, 2009Date of Patent: June 26, 2012Assignee: Amaranth Medical Pte.Inventors: Kamal Ramzipoor, Alfred N. K. Chia, Liwei Wang, Chang Y. Lee
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Patent number: 8206635Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: GrantFiled: June 20, 2008Date of Patent: June 26, 2012Assignee: Amaranth Medical Pte.Inventors: Kamal Ramzipoor, Alfred N. K. Chia, Liwei Wang
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Publication number: 20110302677Abstract: Detection and characterization of laser-induced heat affected zones on polymer based devices, such as polymeric stents, are described where Nano Thermal Analysis may be used with atomic force microscopy to obtain the thermal behavior of materials with a spatial resolution of under, e.g., 100 nm. Heat may be applied locally to the measured polymeric stem via a probe tip and the resulting thermal-mechanical response can be measured.Type: ApplicationFiled: June 3, 2011Publication date: December 8, 2011Applicant: Amaranth Medical PteInventors: Kamal RAMZIPOOR, Yiwen TANG
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Publication number: 20100185270Abstract: Sterilization methods for implantable prostheses are described where a polymeric stent may be sterilized, e.g., via ETO sterilization, at a temperature below a glass transition temperature of the stent. A separate delivery catheter may be sterilized separately and the stent and delivery catheter may then be combined in an aseptic or semi-aseptic environment and sterilized as an assembled system such that the requirements for sterilizing the system are relatively lower. Additionally and/or alternatively, valve and filter assemblies may be used with an optional mandrel assembly for maintaining sterility of the internal components of a catheter system.Type: ApplicationFiled: December 29, 2009Publication date: July 22, 2010Applicant: AMARANTH MEDICAL PTE.Inventors: Kamal Ramzipoor, Chang Yeul Lee, Fozan O. El-Nounou
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Publication number: 20100004734Abstract: Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.Type: ApplicationFiled: June 19, 2009Publication date: January 7, 2010Applicant: Amaranth Medical Pte.Inventors: Kamal RAMZIPOOR, Alfred N. K. CHIA, Liwei WANG, Chang Yeul Lee