Patents Assigned to amaxa GmbH
  • Publication number: 20090023131
    Abstract: The invention relates to a novel circuit arrangement for electrotransfection or electrofusion, which enables the transportation of DNA and/or other biologically active molecules to the nucleus of higher eukaryotic cells or the fusion of cells, independent of cell division and with reduced cell mortality.
    Type: Application
    Filed: August 9, 2007
    Publication date: January 22, 2009
    Applicant: AMAXA GMBH
    Inventors: Herbert Muller-Hartmann, Gudula Riemen, Kirsten Rothmann-Cosic, Corinna Thiel, Ludger Altrogge, Meike Weigel, Rainer Christine, Elke Lorbach, Juliana Helfrich, Heike Wessendorf, Gregor Siebenkotten
  • Publication number: 20070059834
    Abstract: Disclosed is a method for treating biological material via electrical current, in which the biological material is added to a small volume of a buffer solution having relative high ionic strength. A strong electrical field is generated in the buffer solution by a high voltage pulse having a preset duration. The biological material is added to at most 50 ?l of a buffer solution with an ionic strength of at least 100 mmol/l. By at least one voltage pulse having a preset duration of at least 10 ?s, an electrical field with a field strength of at least 1 kV/cm is generated in the buffer solution. The voltage pulse is hereby interrupted at least once for a duration of at least 100 ?s and is then again continued.
    Type: Application
    Filed: June 29, 2006
    Publication date: March 15, 2007
    Applicant: AMAXA GMBH
    Inventors: Herbert Mueller-Hartmann, Michael Habig
  • Publication number: 20060094095
    Abstract: The invention relates to a method for treating biomaterial using at least one electrical field generated by a first voltage pulse which is terminated once the value for an electrical parameter has exceeded or dropped below a preset limit. After the first voltage pulse has been terminated, it is continued by an additional voltage pulse. The invention also relates to a circuit arrangement comprising at least one storage device for electrical charges to generate at least one voltage pulse by selectively discharging the storage device, and at least one control unit for controlling the discharge. The present invention provides a controller for monitoring the chronological progression of the voltage pulse, said controller controlling at least one continuation of discharge after termination.
    Type: Application
    Filed: June 14, 2005
    Publication date: May 4, 2006
    Applicant: amaxa GmbH
    Inventor: Herbert Mueller-Hartmann
  • Publication number: 20060087522
    Abstract: The invention concerns a container 1 with chambers 2 which each comprise at least one pair of electrodes including a first 4 and a second electrode 5 for the application of electric voltage for generating an electric field within one chamber 2. At least two first electrodes 4 of different chambers 3 are conductively coupled and at least one second electrode 5 of said chamber 2 is separately conductively connectable. The invention further concerns a method for manufacturing said container 1 as well as a device for electrically contacting at least one of said containers 1.
    Type: Application
    Filed: March 15, 2005
    Publication date: April 27, 2006
    Applicant: amaxa GmbH
    Inventors: Herbert Muller-Hartmann, Michael Habig
  • Publication number: 20050214562
    Abstract: The invention relates to a method for generating at least one electrically contactable area on a polymer which is doped with a conductive substance, wherein a contact material is applied onto the polymer, which has a lower specific resistance at 23° C. than the polymer. According to the invention the contact material is applied onto the polymer so tightly that close contact between the contact material and the conductive substance is achieved. Due to the tight application of the contact material, which has a lower specific resistance than the polymer, the input resistance of the doped polymer is effectively reduced. The invention further concerns a formed body made of a polymer which is doped with a conductive substance, which has at least one contactable area, within which a contact material is applied onto the polymer, which has a lower specific resistance at 23° C. than the polymer.
    Type: Application
    Filed: October 25, 2004
    Publication date: September 29, 2005
    Applicant: amaxa GmbH
    Inventors: Herbert Muller-Hartmann, Ewald Fernbach, Gregor Siebenkotten