Patents Assigned to Ambrx
  • Modified human growth hormone
    Publication number: 20060189529
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Application
    Filed: December 21, 2005
    Publication date: August 24, 2006
    Applicant: Ambrx, INc.
    Inventors: Ho Cho, Thomas Daniel, Richard DiMarchi, Anna-Maria Hays, Troy Wilson, Bee-Cheng Sim, David Litzinger
  • Methods for expression and purification of recombinant human growth hormone
    Publication number: 20060183198
    Abstract: The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH from recombinant host cells or culture medium including, for example, yeast, insect, mammalian and bacterial host cells. The process of the present invention is also useful for purification of hGH linked to polymers or other molecules.
    Type: Application
    Filed: December 21, 2005
    Publication date: August 17, 2006
    Applicant: Ambrx, Inc.
    Inventors: Ying Buechler, Ricky Lieu, Michael Ong, Stuart Bussell, Nick Knudsen, Ho Cho
  • Novel antigen-binding polypeptides and their uses
    Publication number: 20060153860
    Abstract: Novel antigen-binding polypeptides (ABP) and uses thereof are provided.
    Type: Application
    Filed: June 17, 2005
    Publication date: July 13, 2006
    Applicant: Ambrx, Inc.
    Inventors: Ho Cho, Thomas Daniel, Troy Wilson, Thomas Cujec, Feng Tian, Anna-Maria Hays, Bruce Kimmel, Lillian Ho
  • Formulations of human growth hormone comprising a non-naturally encoded amino acid
    Publication number: 20060135427
    Abstract: Formulations of modified human growth hormone polypeptides are provided.
    Type: Application
    Filed: December 21, 2005
    Publication date: June 22, 2006
    Applicant: Ambrx, Inc.
    Inventors: Anna-Maria Hays, Ying Buechler, David Litzinger
  • Biosynthetic polypeptides utilizing non-naturally encoded amino acids
    Publication number: 20060019347
    Abstract: Modified biosynthetic polypeptide molecules, methods for manufacturing, and uses thereof are provided.
    Type: Application
    Filed: July 21, 2005
    Publication date: January 26, 2006
    Applicant: Ambrx, Inc.
    Inventors: Ho Cho, Thomas Daniel, Anna-Maria Hays, Troy Wilson, David Litzinger, Roberto Mariani, Bruce Kimmel, William Keefe
  • Modified human interferon polypeptides and their uses
    Publication number: 20050220762
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: January 28, 2005
    Publication date: October 6, 2005
    Applicant: Ambrx, Inc.
    Inventors: Ho Cho, Thomas Daniel, Anna-Maria Hays, Troy Wilson
  • Modified human growth hormone polypeptides and their uses
    Publication number: 20050170404
    Abstract: Modified human growth hormone polypeptides and uses thereof are provided.
    Type: Application
    Filed: January 28, 2005
    Publication date: August 4, 2005
    Applicant: Ambrx, Inc.
    Inventors: Ho Cho, Thomas Daniel, Richard DiMarchi, Anna-Maria Hays, Troy Wilson, Bee-Cheng Sim, David Litzinger
  • Polymer derivatives
    Publication number: 20050085619
    Abstract: The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selective incorporation of non-genetically encoded amino acids, e.g., those amino acids containing an azide or acetylene moiety, into proteins in response to a selector codon and the subsequent modification of those amino acids with a suitably reactive PEG derivative.
    Type: Application
    Filed: October 7, 2004
    Publication date: April 21, 2005
    Applicant: Ambrx, Inc.
    Inventor: Troy Wilson