Abstract: The invention relates to Novel DNA and amino acid sequences for a heparin bending neurotrophic factor, (HBNF). Also described are expression vectors and host cells useful in a method for production of the HBNF protein.
Abstract: Insect viruses capable of killing at least one target insect pest quicker than previously described viruses and methods for conferring that phenotype of faster killing are provided. Further improvement in the speed of killing is obtained when the virus of this invention also contains a nonfunctional egt gene to reduce feeding by the infected larvae, inhibit growth and further mediate the earlier death of the infected insect and/or it also contains and expresses a DNA sequence encoding an insect-specific toxin. The faster killing phenotype is achieved by inactivating an ORF 603 of AcMNPV or an ORF 603 homolog of a different species of baculovirus. Improved insecticidal compositions and improved methods of controlling insects are also included within the scope of this invention.
Type:
Grant
Filed:
January 12, 1999
Date of Patent:
December 5, 2000
Assignees:
University of Georgia Research Foundation, American Cyanamid Corporation
Inventors:
Lois K. Miller, Bruce C. Black, Peter M. Dierks, Nancy C. Fleming
Abstract: Certain derivatives of cyclopropane carboxylic acid and their esters are useful and valuable intermediates for the preparation of broad spectrum pyrethroid type pesticides. The invention provides a novel method for the preparation of the derivatives of cyclopropane carboxylic acid and esters from stable sulfonium ylides.