Abstract: There are provided gastric cytoprotective exogenously acidified aluminum hydroxide antacid compositions which are formed by acidifying, for example, commercial liquid antacid suspensions containing aluminum hydroxide, antacid powders or solids containing aluminum hydroxide, or aluminum hydroxide gel, to the point where the aluminum hydroxide is solubilized. The solutuions may be formulated into liquid dosage forms or spray dried and formulated into solid dosage forms.

Abstract: An electrode assembly for sensing heart activity and especially heart activity from a fetal epidermis during the birth of a child. A fetal electrode introducer includes a rigid guide tube with an intermediate universal joint which allows the guide tube to be bent at the best angle to accommodate each patient. The intermediate joint allows a smooth transmission of the rotary motion manually applied at a distal handle to drive the electrode into the fetal epidermis.A sliding sleeve covers the fetal electrode to provide a bearing for rotation, protects the electrode from contamination, and also serves as a resistance means to indicate to the user that the assembly has abutted against the fetal epidermis. Such resisting means includes either a detent or lockable system, or a breakable membrane.

Abstract: The invention provides a transdermal/transmucosal pharmaceutical delivery system having an improved drug reservoir comprising a thin layer of foamed material made from high molecular weight polyethylene, the foamed material having a void volume of at lesat 20% per unit of surface area and a narrow pore size variation per unit of surface area.

Abstract: A pediatric ibuprofen composition is provided wherein the ibuprofen remains in suspension and wherein the bitter taste of ibuprofen is masked, the primary suspending agents being xanthan gum, microcrystalline cellulose, sodium carboxymelthylcellulose and polysorbate, and the primary taste masking agents being sucrose and sorbitol solution.

Abstract: For suppressing cardiovascular artifact from a respiration signal derived from a patient's transthoracic impedance, an adaptive filtering device determines the patient's heart rate, converts the respiration signal from an analog to digital representation at a rate proportional to the heart rate, and then filters the digital respiration signal such that that portion of the respiration signal having a frequency content at or above the heart rate is most greatly attenuated.

Abstract: A therapeutic taste-neutral powder form of acetaminophen obtained by spray-drying a suspension of colloidal silica in a lower alkanol solution of acetaminophen and ethyl cellulose.

Abstract: A therapeutic taste-neutral powder form of acetaminophen obtained by spray-drying a suspension of acetaminophen in a solution of ethylcellulose in an organic solvent selective for ethylcellulose.

Abstract: A therapeutic taste-neutral powder form of acetaminophen obtained by spray-drying a dispersion of acetaminophen and ethyl cellulose in water having a plasticizer dissolved or suspended therein.

Abstract: A therapeutic taste-neutral powder form of acetaminophen obtained by spray-drying a suspension of acetaminophen in a solution of a particular copolymer, cationic in character, based on dimethylaminoethyl methacrylate and neutral methacrylic acid esters.

Abstract: In a device for recording information on strip chart paper, a paper tray, paper guide and door having a trench area are positioned relative to one another to inhibit lateral movement of the paper during recordal of the information. The trench area which is located between the paper storage tray and paper guide receives and traps the paper between its walls to ensure that the paper travels along a predetermined path. The paper storage tray is slightly tilted to further ensure that the paper follows the desired path of travel.

Abstract: A method is disclosed for the prevention and treatment of periodontal disease and alveolar bone loss by administering an effective amount of tolrestat to a human subject.

Abstract: A method is disclosed for inhibiting joint ankylosis for the treatment of arthritides by administering an effective amount of etodolac.

Abstract: A process is provided for preparing 3-hydroxy-3-phenyl-butan-2-one, useful in the preparation of acifran, in high yields by reacting 2,3-butanedione with the appropriate Grignard reagent at low temperature in tetrahydrofuran or admixtures thereof with toluene.

Abstract: A method is disclosed for inhibiting pulmonary hemorrhage and edema associated with intracranial syndromes such as trauma, tumor, hemorrhage and stroke by administering an effective amount of vinpocetine.