Abstract: A system and method for comparing pharmaceutical prices and mediation utilization that provides separate databases containing (i) client pharmaceutical wholesaler and non-wholesaler purchase data, (ii) pharmaceutical compendia information, (iii) client pharmaceutical contract information, (iv) client organizational profile information, and (v) client patient volume and acuity data; and a processor in communication with the databases that (i) uploads the data and information from the databases into an input module that standardizes, validates and merges the data and information, (ii) processes the data and information from the input module by performing pricing and utilization analyses on the information and generating savings opportunities information, and (iii) formats the savings opportunities information and generates and pricing and utilization reports. A database interface for customized reporting and research analytics is also provided.