Patents Assigned to Amersha, Health AS
  • Preparation of 5-amino-isophthalamides
    Patent number: 6441235
    Abstract: A process for preparing 5-amino-N,N′-bis(R)isophthalamides, where A is 2,3-dihydroxypropyl or 1,3-dihydroxyisopropyl, useful as intermediates in preparing iodinated diagnostic agents, which comprises reacting a di-lower-alkyl 5-nitroisophthalate with a compound of the formula RNH2 in the presence of a basic catalyst and without isolating the intermediate 5-nitro-N,N′-bis(R)isophthalamide, catalytically hydrogenating the latter.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: August 27, 2002
    Assignee: Amersha, Health AS
    Inventors: Edward David Parady, Karl Olaf Gelotte