Abstract: Compound comprising agarose covalently bonded to amino phenyl boronic acid through a substituted triazine and an intermediate compound comprising substituted triazine bonded to amino phenyl boronic acid.

Abstract: Glycoproteins, especially glycosylated hemoglobins, are separated from non-glycosylated proteins, by complexing with a dihydroxyboryl reactive agent. The resulting complex can be separated physically from the non-glycosylated protein, making possible the determination of glycosylated hemoglobin content of lysed blood; a reactive agent and a kit are described for use in such determination and as a monitor in the control of diabetic treatment. The invention can also be used preparatively to isolate glycoproteins.

Abstract: Particles having a mean diameter from 0.1 to 50 micrometers and having a solid core of water-impermeable polyacrylonitrile and a partially hydrolyzed hydrophilic surface layer enclosing the core containing from 0.001 to 0.8 milliequivalents of carboxyl or carboxylate groups per dry gram, the surface layer amounting to 0.01 to 20% by weight of the particles, are useful as a solid phase insoluble support to which biospecific reagents such as antigens or antibodies can be coupled. Variants include supports in which N-hydroxysuccinimide or various spacer arms are coupled to the carboxyl or carboxylate groups.

Abstract: Novel thermoplastic curing agents formed by reacting an imidazole compound with an epoxy resin, and with--optionally as a third reactant--polyfunctional proton-donating compounds like polybasic acids or phenolic novolac resins. The curing agents are extraordinary in that they are useful in formulating novel storeable, one-package, heat-curable epoxy resin-based compositions. Moreover, they react synergistically with known curing agents, most notably dicyandiamid. The cured materials are of excellent quality. Processes, whereby the various novel materials of the invention are made, are also described.

Abstract: A process for separating blood plasma from whole blood that dispenses with the known centrifugal-separation techniques and involves passing whole blood along a flow path which is shallow and substantially parallel to the upstream side of filtration membrane, recovering plasma from the downstream side of said membrane, and recovering the retained blood components (formed elements) from the upstream side of the membrane. .Iadd .