Patents Assigned to AmideBio LLC
  • Chemically and thermodynamically stable insulin analogues and improved methods for their production
    Patent number: 9006176
    Abstract: The subject matter of this invention is directed towards chemically and thermodynamically stable single-chain insulin (SCI) analogues that are resistant to deamidation and fibrillation. The invention further discloses improved methods for the recombinant expression, purification and refolding of SCI.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: April 14, 2015
    Assignee: AmideBio LLC
    Inventors: Michael H. B. Stowell, Mikhail Plam
  • CHEMICALLY AND THERMODYNAMICALLY STABLE INSULIN ANALOGUES AND IMPROVED METHODS FOR THEIR PRODUCTION
    Publication number: 20140315798
    Abstract: The subject matter of this invention is directed towards chemically and thermodynamically stable single-chain insulin (SCI) analogues that are resistant to deamidation and fibrillation. The invention further discloses improved methods for the recombinant expression, purification and refolding of SCI.
    Type: Application
    Filed: April 16, 2014
    Publication date: October 23, 2014
    Applicant: AMIDEBIO LLC
    Inventors: Michael H.B. Stowell, Yanyu Peng, Mikhail Plam
  • Efficient production of peptides
    Patent number: 8796431
    Abstract: The present invention relates to processes for the production of peptides, and the peptides produced accordingly. Peptides produced according to the invention may be produced more efficiently than peptides produced according to prior art processes. The production process of the invention may lead to advantages in yield, purity, and/or price. Methods of marketing peptides are also disclosed.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: August 5, 2014
    Assignees: The Regents of the University of Colorado, a body corporate, AmideBio LLC
    Inventors: Michael H. B. Stowell, Jonathan Caruthers, Travis Nemkov, Brian Hiester, Leslie Boux, Mikhail Plam
  • DEUTERATED PEPTIDES
    Publication number: 20140058790
    Abstract: Methods and compositions described herein relate to processes for the production of deuterated peptides, and the deuterated peptides produced accordingly. Deuterated peptides produced according to methods and compositions described herein may be produced more efficiently than such peptides produced according to prior art processes. The production process of according to methods and compositions described herein may lead to advantages in yield, purity, and/or price for deuterated peptides. Methods of marketing deuterated peptides are also disclosed.
    Type: Application
    Filed: November 30, 2011
    Publication date: February 27, 2014
    Applicant: AmideBio LLC
    Inventors: Michael H.B. Stowell, Mikhail Plam
  • Chemically and Thermodynamically Stable Insulin Analogues and Improved Methods for their Production
    Publication number: 20130096057
    Abstract: The subject matter of this invention is directed towards chemically and thermodynamically stable single-chain insulin (SCI) analogues that are resistant to deamidation and fibrillation. The invention further discloses improved methods for the recombinant expression, purification and refolding of SCI.
    Type: Application
    Filed: October 16, 2012
    Publication date: April 18, 2013
    Applicant: AMIDEBIO LLC
    Inventor: AmideBio LLC
  • Efficient Production of Peptides
    Publication number: 20110112990
    Abstract: The present invention relates to processes for the production of peptides, and the peptides produced accordingly. Peptides produced according to the invention may be produced more efficiently than peptides produced according to prior art processes. The production process of the invention may lead to advantages in yield, purity, and/or price. Methods of marketing peptides are also disclosed.
    Type: Application
    Filed: November 9, 2010
    Publication date: May 12, 2011
    Applicants: The Regents of the University of Colorado, a body corporate, AmideBio LLC
    Inventors: Michael H. B. Stowell, Jonathan Caruthers, Travis Nemkov, Brian Hiester, Leslie Boux, Mikhail Plam