Abstract: Computer systems, programs, and methods can advantageously be used to process optical data. These approaches often involve modifying a first format data to a second format data, and are useful in simplifying the complications due to data from different wavefront systems, different aberrometer devices and aberrometer software versions, different clinical studies and different measurement conditions. A centralized database system can be used effectively in a clinical research setting, which can be a medical center, a college, or a research department in a company, or in other diagnosis or treatment facilities.

Abstract: Methods, devices, and systems for predicting an optical acuity measure of an optical system of an eye. An optical acuity measure can be predicted by determining a point spread function based on a wavefront measurement of an eye, convolving a resolution target with the point spread function to produce an image, and predicting the optical acuity measure of the optical system of the eye based on the image.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

Abstract: Devices, systems, and methods control pulse energies of excimer and other lasers, particularly for refractive correction in which a pulse rate, pulse energy, or other parameters of a pulsed laser is varied during use. A calibration laser mode may be used to fire a series of laser pulses to characterize a correlation between laser energy and a laser operation parameter (typically discharge high voltage) throughout a range. During an operation mode, subsequent voltages may be set based on energies of prior pulses while accounting for a curve or change in rate of the correlation.

Abstract: Systems, methods, and software for determining a set of analytical or numerical polynomials that is orthonormal over circular or noncircular pupils are described. Closed-form orthonormal polynomials for circular, annular, hexagonal, elliptical, rectangular, and square pupils are derived. Such techniques can be applied to ray tracing as in the optical design and wavefront fitting from measurement as in the optical testing. These approaches can also be applied to wavefront reconstruction in adaptive optics.

Abstract: Optical correction methods, devices, and systems reduce optical aberrations or inhibit refractive surgery induced aberrations. Error source control and adjustment or optimization of ablation profiles or other optical data address high order aberrations. A simulation approach identifies and characterizes system factors that can contribute to, or that can be adjusted to inhibit, optical aberrations. Modeling effects of system components facilitates adjustment of the system parameters.

Abstract: Devices systems, and methods can characterize an optical surface of an object. A wavefront sensor system focuses light energy propagating from the object to form a pattern on a detector. The system maps the pattern to an array with a transform function such as a Fourier transform. The values of array correspond to characteristic locations and signals in a transform space, for example an intensity of spatial frequency signals in frequency space. The characteristic location and intensity of these signals in transform space are used to measure the optical surface. For example, a characteristic frequency of a spatial frequency intensity peak in Fourier transform space can be used to estimate the location of spots on the detector. Alternatively, the characteristics can be used to the measure sphere, cylinder and axis of a wavefront, wavefront elevation maps and point spread functions, often without locating positions of individual spots on the detector.

Abstract: Devices, systems and methods for scaling the size and/or position of a marker on a magnified image of an object. In preferred embodiments, the object is an eye that is undergoing laser eye surgery. The eye is viewed through a magnification system or microscope and an image of the eye is presented on a display. One or more markers are present on the image, each identifying a specific target location or landmark on the eye. When a desired magnification setting is selected, the image is scaled accordingly. In addition, one or more of the markers is scaled in size and/or position to reflect the magnification setting. This allows the marker to maintain identification of the target location while reflecting the selected magnification level.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

Abstract: Devices systems, and methods can characterize an optical surface of an object. A wavefront sensor system focuses light energy propagating from the object to form a pattern on a detector. The system maps the pattern to an array with a transform function such as a Fourier transform. The values of array correspond to characteristic locations and signals in a transform space, for example an intensity of spatial frequency signals in frequency space. The characteristic location and intensity of these signals in transform space are used to measure the optical surface. For example, a characteristic frequency of a spatial frequency intensity peak in Fourier transform space can be used to estimate the location of spots on the detector. Alternatively, the characteristics can be used to the measure sphere, cylinder and axis of a wavefront, wavefront elevation maps and point spread functions, often without locating positions of individual spots on the detector.

Abstract: Methods, devices, and systems for reprofiling a surface of a cornea of an eye ablate a portion of the cornea to create an ablation zone with an optically correct central optical zone disposed in a central portion of the cornea, and a blend zone disposed peripherally to the central optical zone and at least partially within an optical zone of the eye. The blend zone can have an optical power that gradually diminishes with increasing radius from the central optical zone.

Abstract: Systems and methods for removing an epithelial layer disposed over a stromal layer in a cornea irradiate a region of the epithelial layer with a pulsed beam of ablative radiation. The ablative radiation is scanned to vary the location of the beam within the region in accordance with a pulse sequence. The pulse sequence is arranged to enhance optical feedback based on a tissue fluorescence of the epithelial layer. The penetration of the epithelial layer is detected in response to the optical feedback. The use of scanning with the pulse sequence arranged to enhance optical feedback allows large areas of the epithelium to be ablated such that an operator can detect penetration of the epithelial layer.

Abstract: The present invention generally provides improved devices, systems, and methods for measuring characteristics of at least one eye, and particularly for measuring the physiological changes in eyes under different viewing conditions. An exemplary embodiment provides a pupilometer which measures any changes in location of a pupil center with changes in viewing distances. As the eye often moves significantly during viewing, the pupil center location will often be measured relative to a convenient reference of the eye such as an outer iris boundary. Pupil size may also be recorded, and the measurements from both eyes of a patient may be taken simultaneously. Exemplary embodiments may be configured so as to allow the vergence angle between the eyes to vary with differing viewing distances, regardless of whether one or both eyes are being measured.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

Abstract: Methods, systems and software for determining an optical surface model for an optical tissue system using Fourier transformation algorithms. A method of reconstructing optical tissues an eye comprises transmitting an image through the optical tissues of the eye. The surface gradients from the transmitted image are measured across the optical tissues of the eye. A Fourier transform algorithm is applied to the surface gradients to reconstruct an optical surface model that corresponds to the optical tissues of the eye.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

Abstract: Methods, devices, and systems for reprofiling a surface of a cornea of an eye ablate a portion of the cornea to create an ablation zone with an optically correct central optical zone disposed in a central portion of the cornea, and a blend zone disposed peripherally to the central optical zone and at least partially within an optical zone of the eye. The blend zone can have an optical power that gradually diminishes with increasing radius from the central optical zone.

Abstract: Systems and methods provide for stabilizing the amount of laser energy delivered to a target from a laser device. Generally, delivered laser energy is measured over multiple laser pulses or over time in the case of a constant wave laser. A decrease is then calculated in the delivered energy, the decrease being caused by accumulation of one or more substances, such as ozone, along the laser beam delivery path due to passage of the laser beam along the path. Using this calculated decrease, a laser device may be adjusted to compensate for the decrease in delivered energy due to the accumulated substance(s), thus stabilizing the amount of energy delivered to the target.

Abstract: Devices, systems, and methods for laser eye surgery selectively ablate tissues within the cornea of an eye along one or more target surfaces, so that corneal tissue bordered by the laser incision surface(s) can be mechanically removed. An appropriate tissue-shaping surface can be selected based on the regular refractive error of the eye, and a shape of the target laser surface(s) can be calculated so as to correct irregular refractive errors of the eye, impose desired additional sphero-cylindrical and/or irregular alterations.