Patents Assigned to Amphera B.V.
  • PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OF CANCER
    Publication number: 20230256066
    Abstract: The present invention relates to an antigen composition comprising at least one mesothelioma cancer cell associated antigen and a pharmaceutically acceptable carrier for use in the treatment of cancer, in particular mesothelioma, wherein dendritic cells are loaded with said antigen composition and wherein said loaded dendritic cells are administered in combination with one or more checkpoint inhibitors, to patients. The present invention also relates to an antigen composition comprising at least two mesothelioma cancer cell associated antigens and a pharmaceutically acceptable carrier. The present invention further relates to an antigen composition comprising at least two mesothelioma cancer cell associated antigens and a pharmaceutically acceptable carrier, for use as a pharmaceutical, in particular for use in the treatment of mesothelioma.
    Type: Application
    Filed: March 8, 2023
    Publication date: August 17, 2023
    Applicant: AMPHERA B.V.
    Inventor: Joan Geertrudis Jacobus Victor AERTS
  • Method for preparing an immunogenic lysate, the lysate obtained, dendritic cells loaded with such lysate and a pharmaceutical composition comprising the lysate or the dendritic cells
    Patent number: 11278605
    Abstract: The present invention relates to a method for the preparation of an immunogenic lysate from mesothelioma tumor cells, to such a lysate and to dendritic cells loaded with the lysate, the present invention further relates a pharmaceutical composition comprising such lysate or dendritic cells, to the use of the lysate, and to said loaded dendritic cells or said pharmaceutical composition for use in the prevention or treatment of mesothelioma.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: March 22, 2022
    Assignee: AMPHERA B.V.
    Inventors: Josephus Petrus Johannes Jacobus Hegmans, Joan Geertrudis Jacobus Victor Aerts
  • METHOD FOR PREPARING AN IMMUNOGENIC LYSATE, THE LYSATE OBTAINED, DENDRITIC CELLS LOADED WITH SUCH LYSATE AND A PHARMACEUTICAL COMPOSITION COMPRISING THE LYSATE OR THE DENDRITIC CELLS
    Publication number: 20180296654
    Abstract: The present invention relates to a method for the preparation of an immunogenic lysate from mesothelioma tumor cells, to such a lysate and to dendritic cells loaded with the lysate, the present invention further relates a pharmaceutical composition comprising such lysate or dendritic cells, to the use of the lysate, and to said loaded dendritic cells or said pharmaceutical composition for use in the prevention or treatment of mesothelioma.
    Type: Application
    Filed: April 3, 2018
    Publication date: October 18, 2018
    Applicant: Amphera B.V.
    Inventors: Josephus Petrus Johannes Jacobus HEGMANS, Joan Geertrudis Jacobus Victor AERTS
  • Method for preparing an immunogenic lysate, the lysate obtained, dendritic cells loaded with such lysate and a pharmaceutical composition comprising the lysate or the dendritic cells
    Patent number: 9962433
    Abstract: The present invention relates to a method for the preparation of an immunogenic lysate from mesothelioma tumor cells, to such a lysate and to dendritic cells loaded with the lysate, the present invention further relates a pharmaceutical composition comprising such lysate or dendritic cells, to the use of the lysate, and to said loaded dendritic cells or said pharmaceutical composition for use in the prevention or treatment of mesothelioma.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: May 8, 2018
    Assignee: Amphera B.V.
    Inventors: Josephus Petrus Johannes Jacobus Hegmans, Joan Geertrudis Jacobus Victor Aerts
  • METHOD FOR PREPARING AN IMMUNOGENIC LYSATE, THE LYSATE OBTAINED, DENDRITIC CELLS LOADED WITH SUCH LYSATE AND A PHARMACEUTICAL COMPOSITION COMPRISING THE LYSATE OR THE DENDRITIC CELLS
    Publication number: 20150352200
    Abstract: The present invention relates to a method for the preparation of an immunogenic lysate from mesothelioma tumor cells, to such a lysate and to dendritic cells loaded with the lysate, the present invention further relates a pharmaceutical composition comprising such lysate or dendritic cells, to the use of the lysate, and to said loaded dendritic cells or said pharmaceutical composition for use in the prevention or treatment of mesothelioma.
    Type: Application
    Filed: December 20, 2013
    Publication date: December 10, 2015
    Applicant: Amphera B.V.
    Inventors: Josephus Petrus Johannes Jacobus HEGMANS, Joan Geertrudis Jacobus Victor AERTS