Patents Assigned to AMPHISTA THERAPEUTICS LIMITED
  • Bifunctional molecules for targeting Rpn11
    Patent number: 11925690
    Abstract: The invention provides for bifunctional molecules comprising an Rpn11 binding partner and a target protein binding partner. A bifunctional molecule according to the invention binds to Rpn11 and to the target protein, thereby facilitating degradation of the target protein bound to the target protein binding partner. The invention also provides for use of a bifunctional molecule for preventing or treating disease.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: March 12, 2024
    Assignee: AMPHISTA THERAPEUTICS LIMITED
    Inventors: Alessio Ciulli, Andrea Testa, Scott Hughes, Steven Peter Butcher