Patents Assigned to Amplimed, Inc.
  • Cyanoaziridines for treating cancer
    Patent number: 6297230
    Abstract: The present invention is directed to novel anti-cancer compounds of the formula. wherein X is CN, R4 is hydrogen or lower alkyl; and R5 is lower alkyl, lower cycloalkyl, alkenyl, alkynyl, aryl, monosubstituted aryl, disubstituted aryl, aryl lower alkyl, lower alkoxycarbonyl lower alkyl, or heterocyclic ring, with the proviso that when X is CN, and R4 is hydrogen, then R5 is not CH3, C6H5, or, p-nitrophenyl. R4, R5 and N taken together form a heterocyclic ring.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: October 2, 2001
    Assignee: Amplimed, Inc.
    Inventors: William A. Remers, Evan M. Hersh, Robert T. Dorr, Bhashyam Iyengar