Patents Assigned to Amydis, Inc.
  • Phosphate compounds for detecting neurological disorders
    Patent number: 12708676
    Abstract: Provided herein are compounds, methods and compositions for determining whether a patient has a neurological disease or disorder is provided, comprising detecting the presence of a detectable target protein, or an accumulated mass thereof, for example, amyloid beta protein or phosphorylated tau protein, or an accumulated mass thereof, in a tissue or a sample of the patient. The detecting may comprise contacting the target protein with a compound described herein.
    Type: Grant
    Filed: March 30, 2023
    Date of Patent: August 18, 2026
    Assignee: Amydis, Inc.
    Inventors: Stella Sarraf, Lyndsay M. Randolph, Suhail Rasool
  • Compositions and methods for detection of traumatic brain injury
    Patent number: 12478693
    Abstract: The present disclosure relates generally to compositions and methods for determining whether a patient suffers from a traumatic brain injury (TBI) by detecting the presence of an amyloid beta protein in an eye of the patient. Also provided are compositions and methods for preparing a patient for diagnosis and treatment of traumatic brain injury (TB).
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: November 25, 2025
    Assignee: Amydis, Inc.
    Inventors: Stella Sarraf, Lyndsay M. Randolph, Suhail Rasool
  • Amyloid targeting agents and methods of using the same
    Patent number: 11718596
    Abstract: Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are methods for treating diseases associated with amyloid or amyloid like proteins.
    Type: Grant
    Filed: February 9, 2021
    Date of Patent: August 8, 2023
    Assignees: The Regents of the University of California, Amydis, Inc.
    Inventors: Jerry Yang, Emmanuel A. Theodorakis, Stella Sarraf
  • Amyloid targeting agents and methods of using the same
    Patent number: 10934264
    Abstract: Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are methods for treating diseases associated with amyloid or amyloid like proteins.
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: March 2, 2021
    Assignees: The Regents of the University of California, Amydis, Inc.
    Inventors: Jerry Yang, Emmanuel A. Theodorakis, Stella Sarraf
  • Amyloid targeting agents and methods of using the same
    Patent number: 10005745
    Abstract: Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are the methods for treating of diseases associated with an amyloid or amyloid like proteins.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: June 26, 2018
    Assignees: The Regents Of The University Of California, Amydis, Inc.
    Inventors: Jerry Yang, Emmanuel A. Theodorakis, Stella Sarraf