Abstract: Cell therapy comprises encapsulating a cell with an integrin or other cell interaction factor, for administration to a mammal. The cells may express a therapeutic transgene or the cells may be regenerative.

Abstract: A catheter assembly especially adapted for injecting therapeutic liquids such as DNA solutions to a patient's myocardium comprises an elongated guiding catheter for insertion through a patient's artery to the vicinity of the myocardium, a reservoir for therapeutic liquid at the distal end of the guiding catheter, one or more injection needles protruding from the distal end of the guiding catheter and in fluid communication with the reservoir, the extent of needle protrusion being appropriate for penetration of but not passage through the myocardial wall, and an operating device for delivering a predetermined quantity of therapeutic liquid from the reservoir through the needles.