Abstract: Sustained and enhanced antipyretic response is elicited in a mammalian organism in need of such treatment, i.e., a mammal suffering from elevated body temperature (fever), by administering thereto a unit dosage sustainedly enhancing, antipyretically effective amount of the free acid S(+) flurbiprofen enantiomer, said enantiomer being substantially free of its R(-) flurbiprofen antipode.
Abstract: Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with at least one other active component selected from an antihistamine, decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold and cold-like symptoms.
Type:
Grant
Filed:
November 20, 1989
Date of Patent:
June 18, 1991
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Pharmaceutical compositions and methods of using same comprising aspirin, sodium salicylate, salicylamide or acetaminophen, in combination with a non-sedating antihistamine and optionally one or more other active components selected from a decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold, cold-like and/or flu symptoms and the discomfort, pain, headache, fever and general malaise associated therewith.
Type:
Grant
Filed:
February 24, 1989
Date of Patent:
December 4, 1990
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Onset-hastened and enhanced antipyretic response is elicited in a human mammal in need of such treatment, i.e., a human mammal suffering from elevated body temperature (fever), by administering thereto a unit dosage onset-hastening/enhancing antipyretically effective amount of the S(+) ketoprofen enantiomer, said enantiomer being substantially free of its R(-) ketoprofen antipode.
Abstract: Sustained and enhanced analgesic response is elicited in a mammalian organism in need of such treatment, i.e., a mammal suffering pain, by administering thereto a unit dosage sustainedly enhancing, analgesically effective amount of the free acid S(+) flurbiprofen enantiomer, said enantiomer being substantially free of its R(-) flurbiprofen antipode.
Abstract: Novel pharmaceutical analgesic, anti-inflammatory and skeletal muscle relaxant compositions and methods of using same comprising an analgesically and anti-inflammatory effective amount of at least one non-steroidal anti-inflammatory drug other than aspirin, acetaminophen and phenacetin, in combination with an effective amount of a skeletal muscle relaxant.
Type:
Grant
Filed:
August 3, 1988
Date of Patent:
May 8, 1990
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with at least one other active component selected from an antihistamine, decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold and cold-like symptoms.
Type:
Grant
Filed:
January 15, 1988
Date of Patent:
April 24, 1990
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Onset-hastened and enhanced analgesic response is elicited in a mammalian organism in need of such treatment, i.e., a mammal suffering pain, by administering thereto a unit dosage onset-hastening/enhancing analgesically effective amount of the S(+) fenoprofen enantiomer, said enantiomer being substantially free of its R(-) fenoprofen antipode.
Abstract: Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with a non-sedating antihistamine and optionally one or more other active components selected from a decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold, cold-like and/or flu symptoms and the discomfort, pain, headache, fever and general malaise associated therewith.
Type:
Grant
Filed:
August 11, 1988
Date of Patent:
October 3, 1989
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Onset-hastened and enhanced analgesic response is elicited in a mammalian organism in need of such treatment, i.e., a mammal suffering pain, by administering thereto a unit dosage onset-hastening/enhancing analgesically effective amount of the S(+) ketoprofen enantiomer, said enantiomer being substantially free of its R(-) ketoprofen antipode.
Abstract: Onset-hastened and enhanced analgesic response is elicited in a mammalian organism in need of such treatment, i.e., a mammal suffering pain, by administering thereto a unit dosage onset-hastening/enhancing analgesically effective amount of the S(+) ibuprofen enantiomer, said enantiomer being substantially free of its R(-) ibuprofen antipode.
Abstract: Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with at least one other active component selected from an antihistamine, decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold and cold-like symptoms.
Type:
Grant
Filed:
March 22, 1988
Date of Patent:
June 20, 1989
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with at least one other active component selected from an anti-histamine, decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold and cold-like symptoms.
Type:
Grant
Filed:
February 19, 1987
Date of Patent:
June 13, 1989
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Pharmaceutical compositions and methods of using same comprising aspirin, sodium salicylate, salicylamide or acetaminophen, in combination with a non-sedating antihistamine and optionally one or more other active components selected from a decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold, cold-like and/or flu symptoms and the discomfort, pain, headache, fever and general malaise associated therewith.
Type:
Grant
Filed:
June 8, 1987
Date of Patent:
May 9, 1989
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with a non-sedating antihistamine and optionally one or more other active components selected from a decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold, cold-like and/or flu symptoms and the discomfort, pain, headache, fever and general malaise associated therewith.
Type:
Grant
Filed:
April 24, 1987
Date of Patent:
November 8, 1988
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Novel pharmaceutical analgesic, anti-inflammatory and skeletal muscle relaxant compositions and methods of using same comprising an analgesically and anti-inflammatory effective amount of at least one non-steroidal anti-inflammatory drug other than aspirin, acetaminophen and phenacetin, in combination with an effective amount of a skeletal muscle relaxant.
Type:
Grant
Filed:
October 30, 1987
Date of Patent:
October 25, 1988
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Novel analgesic and anti-inflammatory compositions of matter for use in eliciting an analgesic or anti-inflammatory response, said compositions comprising caffeine together with a selected non-narcotic analgesic/nonsteroidal anti-inflammatory drug or a selected narcotic analgesic, or both, are disclosed. When used in combination with the selected drugs, caffeine enhances the analgesic or anti-inflammatory response and also hastens its onset.
Type:
Grant
Filed:
March 2, 1987
Date of Patent:
October 11, 1988
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with at least one other active component selected from an antihistamine, decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold and cold-like symptoms.
Type:
Grant
Filed:
February 19, 1987
Date of Patent:
June 7, 1988
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with at least one other active component selected from an antihistamine, decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold and cold-like symptoms.
Type:
Grant
Filed:
February 19, 1987
Date of Patent:
June 7, 1988
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel
Abstract: Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with at least one other active component selected from an antihistamine, decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold and cold-like symptoms.
Type:
Grant
Filed:
February 19, 1987
Date of Patent:
June 7, 1988
Assignee:
Analgesic Associates
Inventors:
Abraham Sunshine, Eugene M. Laska, Carole E. Siegel