Abstract: The present description relates to a method based on artificial intelligence to implement a wide range of microelectronic circuits that can adapt by themselves to the usage conditions (e.g. loading changes), manufacturing variances or defects (e.g. process variations, device parameter mismatches, device model inaccuracies or changes, etc.), as well as environmental conditions (e.g. voltage, temperature, interference) in order to negate all or part of their effects on the circuit performance characteristics and achieve a very tight set of specifications over the wide range of conditions. Each microelectronic circuit is represented by a neural network model whose behavior is a function of the actual input signals, the usage and environmental conditions.