Abstract: Use of (S,S)-N,N'-ethylenediamine disuccinate (EDDS) of formula I wherein M.dbd.H.sup.+ and/or any pharmaceutically acceptable cation, for the preparation of a medicament for the treatment of cytomegaloviral infections which has immunosuppressive properties.
Type:
Grant
Filed:
January 19, 1999
Date of Patent:
October 31, 2000
Assignee:
AnalytiCon AG Biotechnologie Pharmazie
Inventors:
Hans Wilhelm Doerr, Kai Uwe Bindseil, Lutz Muller-Kuhrt, Holger Rabenau, Jindrich Cinatl
Abstract: The invention concerns an HPLC-based device and method for separating high complex substance mixtures. Plant and microbial extracts are high complex substance mixtures. They contain large amounts of extremely polar and non-polar materials. In principle, said mixtures can be separated by using a chromatic method. However, separation with existing chromatographic devices, for instance HPLC installations, is extremely time-consuming. The invention seeks to create a HPLC installation that separates fully automatically high complex substances in a very short time in such a way that said substances are broken down into their components in an almost pure state and can then be fed into a test system. To this end, said HPLC-based device comprises separation column units (A, F),fractionating column units (E, G), detector units (7, and 20, 21), pumping units (B, C, D) and fraction collecting units.