Abstract: Chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3?-position, their bioconjugates and their uses are described. 1,3?-crosslinked carbocyanines are superior to those of conjugates of spectrally similar 1,1?-crosslinked or non-crosslinked dyes. The invention includes derivative compounds having one or more benzo nitrogens.
Type:
Application
Filed:
July 26, 2011
Publication date:
March 1, 2012
Applicant:
AnaSpec Incorporation
Inventors:
Zhenjun Diwu, Jianheng Zhang, Yi Tang, Xiang Guobing
Abstract: Chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3?-position, their bioconjugates and their uses are described. 1,3?-crosslinked carbocyanines are superior to those of conjugates of spectrally similar 1,1?-crosslinked or non-crosslinked dyes. The invention includes derivative compounds having one or more benzo nitrogens.
Type:
Application
Filed:
July 25, 2011
Publication date:
February 23, 2012
Applicant:
AnaSpec Incorporation
Inventors:
Zhenjun Diwu, Jianheng Zhang, Yi Tang, Xiang Guobing