Abstract: This invention relates to compounds of formula (I) and salts, solvates, tautomers, N-oxides, stereoisomers, polymorphs and/or prodrugs thereof. Also disclosed is the use of the compounds of formula (I) to treat necroptosis and/or inhibit MLKL.
Type:
Grant
Filed:
June 18, 2021
Date of Patent:
March 24, 2026
Assignee:
Anaxis Pharma Pty Ltd
Inventors:
Jean-Marc Daniel Garnier, Martin Brzozowski, John Thomas Feutrill, Guillaume Laurent Lessene, Christopher Gardner, Peter Edward Czabotar, Angus Cowan, Katherine Davies, Pooja Sharma, Carole Annie Schuster-Klein, Christophe Poitevin