Abstract: The present disclosure relates to novel therapies and associated methods of treatment based on newly provided therapeutic mechanisms mediated by the binding of glucocorticoids to intercellular adhesion molecules (ICAMs).

Abstract: A magnetic assembly formed by a custom magnetic core and its bobbin with interconnection pins is presented. This magnetic assembly leads to a higher power density of magnetic assembly and a better utilization of the volume inside a power converter, allowing a higher power density of the power converter and a higher efficiency through the minimization of the parasitic inductances.

Abstract: A resonant drive circuit for a capacitive sensor device includes a resonant LC stage, a signal source, and an amplifier stage. The resonant LC stage includes an inductorless floating gyrator circuit electrically connected to a sense capacitor. The inductorless floating gyrator circuit is configured to synthesize a fixed inductance. The resonant LC stage is configured to output a sensed capacitance signal based on the fixed inductance and a change in capacitance of the sense capacitor. The signal source is configured to output a reference signal. The amplifier stage is configured to receive the sensed capacitance signal and the reference signal and output a measured capacitance signal that indicates a difference in one or more of amplitude and phase between the sensed capacitance signal and the reference signal.

Abstract: A rack system for a commercial vehicle including at least one guide rail fixable to at least one vehicle structure of the commercial vehicle, and at least one rack slidingly supported by the guide rail back and forth in a lateral direction of the commercial vehicle. To laterally balance a loading of the commercial vehicle the rack system comprises at least one fixing unit for temporary fixing the rack selectively in one of several fixing positions disposed along the guide rail by fixing the rack to the guide rail and/or to the vehicle structure.

Abstract: The methods and systems relate to improvements to threat modeling systems through the use of crowdsourcing. Specifically, the methods and systems relate to generating recommendations based on crowdsourced threat modeling contributions. For example, the methods and systems automate the threat modeling process by leveraging data in order to drive consistent and measurable quality of threat models and enable threat models to provide aggregated views of risk concentration at any altitude.

Abstract: A two-piece current collector sub-assembly includes a current collector bridge disposed on the positive terminal of a first battery cell and a current collector plate disposed on a second battery cell. The current collector plate surrounds a positive terminal of the second battery cell. The current collector bridge is coupled to the current collector plate to electrically connect the first battery cell to the second battery cell.

Abstract: The present invention is a portable, intelligent, ergonomically adjustable body-seat cushion controlled wirelessly via a smartphone or tablet app. Multiple air bladders embedded in the body-seat cushion inflate/deflate at the direction of the app to manipulate the physical position of the user's neck, back, posterior, legs, and feet in order to: (1) alleviate pressure on the back and sit-bones; (2) lengthen the user from a normal sitting position to a lengthened sitting position; and (3) increase blood flow to the user's extremities. Positioning algorithms in the app use the user's anthropometric data (body measurements) and seat measurements (including available space above and in front of the seat) to generate one or more air bladder fill instructions to lengthen the user. The app then wirelessly transmits the positioning instructions as well as optional motion, temperature, and vibration instructions to one or more wireless receivers in the seat cushion.

Abstract: Presented are intelligent vehicle systems for off-road driving incident prediction and assistance, methods for making/operating such systems, and vehicles networking with such systems. A method for operating a motor vehicle includes a system controller receiving geolocation data indicating the vehicle is in or entering off-road terrain. Responsive to the vehicle geolocation data, the controller receives, from vehicle-mounted cameras, camera-generated images each containing the vehicle's drive wheel(s) and/or the off-road terrain's surface. The controller receives, from a controller area network bus, vehicle operating characteristics data and vehicle dynamics data for the motor vehicle. The camera data, vehicle operating characteristics data, and vehicle dynamics data is processed via a convolutional neural network backbone to predict occurrence of a driving incident on the off-road terrain within a prediction time horizon.

Abstract: A switchable antenna comprises an RF port, an antenna array that includes at least a first column of radiating elements, a second column of radiating elements and a third column of radiating elements, and a feed network coupled between the RF port and the antenna array. The feed network includes a first switch having a first output that is coupled to each of the columns of radiating elements and a second output and a second switch having a first input coupled to the first output of the first switch and a second input coupled to the second output of the first switch, and a first output coupled to the second column of radiating elements.

Abstract: Invented are compounds of formula I and the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are DGAT2 inhibitors. Also provided are methods of making compounds of Formula I, pharmaceutical compositions comprising compounds of Formula I, and methods of using these compounds to treat hepatic steatosis, nonalcoholic steatohepatitis (NASH), fibrosis, type-2 diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, cognitive decline, dementia, cardiorenal diseases such as chronic kidney diseases and heart failure and related diseases and conditions, comprising administering a compound of Formula I to a patient in need thereof.

Abstract: A test apparatus for simulating road conditions for a motor vehicle. The test apparatus includes a platform, a pair of roller assemblies, and a driveshaft. The pair of roller assemblies are coupled to the platform. Each pair of roller assemblies being configured to receive a pair of wheels of the motor vehicle. The driveshaft is secured between the pair of roller assemblies and is configured to transmit rotary power from one of the pair of roller assemblies to the other of the pair of roller assemblies. An orientation of the platform is adjustable.

Abstract: A torque sensor for a bicycle includes a coil. The torque sensor may include a support that is disposable around a device of the bicycle, such that the support and the device of the bicycle are separated by an air gap. The torque sensor may also include an excitation coil supported by the support, and a sense coil supported by the support at a distance away from the excitation coil in an axial direction of the support. The excitation coil is configured to induce a voltage and/or current in the sense coil via the device of the bicycle when the support is disposed around the device of the bicycle. The induced voltage is related to a torque in the device.

Abstract: The present disclosure relates to improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates.

Abstract: Helper neural network can play a role in augmenting authentication services that are based on neural network architectures. For example, helper networks are configured to operate as a gateway on identification information used to identify users, enroll users, and/or construct authentication models (e.g., embedding and/or prediction networks). Assuming, that both good and bad identification information samples are taken as part of identification information capture, the helper networks operate to filter out bad identification information prior to training, which prevents, for example, identification information that is valid but poorly captured from impacting identification, training, and/or prediction using various neural networks. Additionally, helper networks can also identify and prevent presentation attacks or submission of spoofed identification information as part of processing and/or validation.

Abstract: At least one exemplary embodiment is directed to earpiece devices that share information with other earpiece devices within range (e.g., GPS location and identity). For example multiple users can send signals to each individual earpiece when in range or to a mobile audio communications device via a wireless connection with each earpiece.

Abstract: A robot assembly operable to couple to one or more accessories including a housing coupled with two wheels and at least one electric motor operably coupled with the plurality of wheels. A navigation system can have one or more sensors operably disposed within the housing and the navigation system can be operable to receive data from the one or more sensors and communicatively couple with the at least one electric motor.

Abstract: A session management function (SMF) receives, from a wireless device, a protocol data unit (PDU) session establishment request message including a parameter indicating a request for synchronization of multiple data flows. The session management function sends, to a user plane function (UPF) and based on the parameter, a user plane rule indicating that the UPF performs synchronized forwarding of packets of the multiple data flows.

Abstract: A static battery with a non-conductive elastomeric or thermoplastic housing. The, battery housing is adapted to receive at least one anode assembly, at least one cathode assembly, and at least one bipolar electrode assembly. At least the bipolar electrode assembly is formed from a conductive plastic resin that is formed as a CPE sheet. A carbon material is affixed to the CPE sheet to form the bipolar electrode. The at least one cathode assembly, the at least one anode assembly and the at least one bipolar electrode assembly are received into the battery box such that a liquid, and/or gas seal is formed, between electrode assemblies. The battery housing has slots into which the electrode assemblies are received. When the electrode assemblies are received into the housing, cells are formed by the cooperation of the electrode assemblies and the battery housing. The cells are then filled with electrolyte such as zinc bromide and a lid is placed on the battery box.

Abstract: Water or wastewater filtration systems and processes have a filter tank having a floor and sidewall defining a filtration zone, an influent conduit, and an effluent conduit. One or more filtration members in the tank having filter media, and one or more cleaning members adjacent at least some portions of the filter media. Generating an effluent stream by generating a pressure differential across submerged portions of the filtration media, causing water in the influent to flow from outside to inside the submerged portions of the filter media. A prime mover rotates the filtration members. A blower and chamber for creating a reduced pressure condition in each of the cleaning members when they are non-submerged, the chamber receiving wet solids removed from non-submerged, wet solids-laden portions of the filter media by the non-submerged cleaning members subsequent to submerged, fouled portions of the filter media being rotated out of the filtration zone.

Abstract: Disclosed herein are aspects of expandable interbody devices having an unobstructed graft material containment space. Such expandable interbody devices have a structure in which an overall plan view area of the graft material containment space is devoid of elements of the expandable interbody device enabling adjustment of the expandable interbody devices between a collapsed configuration and displaced configuration (e.g., an expanded configuration and/or a tilted configuration). In this manner, expandable interbody devices configured in accordance with embodiments of the disclosures made herein do not have obstructions within the graft material containment space thereof that limit the available volume of graft material and associated bony material growth that may be contained within the graft material containment space.