Abstract: Provided are a 3Clpro protease inhibitor, a pharmaceutical composition containing the compound of formula (I), and a method for treating coronavirus by using the compound.

Abstract: Scents are perceived by the olfactory sensory neurons (OSNs) that line the upper nasal cavity. Each OSN expresses one odorant receptor, and these odorant receptors contact the scent molecules. Methods for determining which odorant receptor(s) are activated by a scent are lacking, making it difficult to replicate or improve scents. The technology as disclosed herein refers to methods relating to activating odor response genes found in olfactory sensory neurons after the neurons are exposed to at least one volatilized chemical compound.

Abstract: A method of making an aluminum-cubic boron nitride (Al-cBN) composite includes mixing an aluminum powder and particles of cubic boron nitride (cBN) in a solvent and sonicating to form an Al-cBN mixture; drying the Al-cBN mixture to form a dried mixture powder; and sintering by pressing and heating the dried mixture powder to form the Al-cBN composite. The aluminum powder has an average particle size of 10 to 100 micrometers (?m). The cBN particles have an average particle size of from 10 to 100 ?m, and are uniformly dispersed throughout the Al-cBN composite.

Abstract: An object of the present disclosure is to enable extraction of a point cloud of a linear object such as a cable having a sparse point cloud. The present disclosure is a device and a method in which point cloud data representing three-dimensional coordinates and a movement track at the time of measuring the point cloud data are acquired, and the number of point clouds within a certain distance DN from the point cloud on the movement track is repeatedly counted to extract a point cloud of a linear object such as a cable 92.

Abstract: The present disclosure provides a satellite switching technique in a non-terrestrial network. A method of a terminal may comprise: obtaining, from a first satellite, uplink (UL) timing advance (TA)-related information for a second satellite; performing satellite switching from the first satellite to the second satellite; and performing communication with the second satellite based on the UL TA-related information.

Abstract: The present invention features novel peripherally-restricted non-benzodiazipene analogs with reduced blood brain barrier permeability and methods of use thereof for reducing tactile dysfunction, social impairment, and anxiety in a subject diagnosed with Autism Spectrum Disorder, Rett syndrome, Phelan McDermid syndrome, or Fragile X syndrome, or for treating touch over-reactivity, pain, or mechanical allodynia.

Abstract: A power circuit includes a power input terminal, a power factor correction circuit, a DC-DC conversion circuit and a power output terminal connected in sequence. The power factor correction circuit includes an input rectifier unit, a first inductor, a first diode, a first capacitor, a power switch transistor, and a rheostat unit.

Abstract: A polymeric compound is disclosed herein, having the general formula I: wherein m, n, X, Y, Z and L are as defined herein. Further disclosed herein are lipid bilayers comprising at least one bilayer-forming lipid and the aforementioned polymeric compound, and liposomes comprising such a bilayer, as well as methods, uses and compositions utilizing such bilayers and/or liposomes for reducing a friction coefficient of a surface and/or for inhibiting biofilm formation.

Abstract: A method and apparatus of OFDR are disclosed, in which a pair of probe signals are launched, on mutually orthogonal channels, into the optical fiber cable that is to be monitored. In a digital processing circuit, phase noise is cancelled from the return signals after detecting them in their respective mutually orthogonal channels and after demodulating them, by combining them such that noise components of the respective demodulated signals are mutually cancelled. In embodiments, a conjugate pair of probe signals are launched, on mutually orthogonal channels, into the optical fiber cable.

Abstract: A method of enhanced oil recovery in a carbonate rock formation including injecting a mixture into the carbonate rock formation containing an oil composition and extracting the oil composition from the carbonate rock formation. The mixture includes 90-99.99 vol % of an aqueous solution and 0.01-10 vol % of a gemini cationic surfactant based on a total volume of the mixture and 1-2000 parts per million (ppm) of methylene blue, based on a total weight of the mixture. During the injecting at least a portion of the gemini cationic surfactant is adsorbed onto the carbonate rock formation, and at least 50% less by volume of the gemini cationic surfactant adsorbs onto the carbonate rock formation compared to a method under the same conditions but without the methylene blue.

Abstract: An objective lens for a charged particle beam apparatus that provides a charged particle beam to a sample, includes: a first electrode exposed to face a sample; a second electrode configured to focus a charged particle beam to the sample; a third electrode comprising a conical tip and a body extending from the tip; and a fourth electrode located in the body of the third electrode. Each of the first electrode, the second electrode, the third electrode, and the fourth electrode has a through-hole, and the charged particle beam is provided to the sample through the through-hole in response to a voltage applied.

Abstract: A system for monitoring glucose concentration that includes a sample holder configured to contain a sample and a radio frequency transmitter configured to emit microwave radiation through the sample. The radio frequency transmitter comprising a radio frequency generator and a first antenna. The radio frequency receiver is configured to receive microwave radiation transmitted from the radio frequency transmitter and passed through the sample, and convert the microwave radiation passed through the sample to an analog signal. The radio frequency receiver comprising a second antenna. The system also includes an analog readout circuit configured to receive the analog signal and process the analog signal into a modified analog signal, and a digital signal processing circuit configured to receive the modified analog signal, convert the modified analog signal into a digital signal, and determine the glucose concentration of the sample from the digital signal.

Abstract: An ultra-wide angle broadband polarization imaging system based on a metasurface, and a detection apparatus, the imaging system comprising a first lens (L1) having negative optical power, a linear polarizer (P1), a quarter wave plate (P2), a diaphragm (STO), a second lens (L2) having positive optical power, a third lens (L3) having positive optical power, and the metasurface (M), wherein an object side surface and an image side surface of the lens are planar or spherical; and the phase distribution required for the system in a broadband spectrum band is achieved by setting different rotation angles ? of a unit structure of the metasurface.

Abstract: A composite additive for forming inclusions with a core-shell structure, a preparation method and a smelting method are provided. The composite additive includes the following chemical components by mass percentage: Fe: 41-59%, Zr: 5-11%, Ti: 14-26%, Mg: 11-19%, and RE: 4-10%, in which the mass percentage content of Zr element, Ti element, Mg element and RE element satisfies a formula: (Ti+Mg+RE)/Zr=4-8. The composite additive for forming inclusions with a core-shell structure has the characteristics of fineness, spheroidization and obvious dispersion effect. This type of inclusions has a bulk modulus similar to that of the iron matrix, which can significantly improve the plasticity, toughness, fatigue resistance, local corrosion resistance, welding performance, cold bending performance, etc. of steel materials, suitable for steel types with strict requirements on the shape of inclusions, such as marine steel, pipeline steel, container steel, cold heading steel, tool and die steel, etc.

Abstract: An object of the present disclosure is to propose a technology that can allow even non-specialists to easily identify driving forces (DF) in order to support the creation of scenarios in line with the actual situation of a company.

Abstract: The present invention provides a pharmaceutical composition which causes skipping of the 53rd exon in the human dystrophin gene with a high efficiency. The present invention provides an oligomer which efficiently enables to cause skipping of the 53rd exon in the human dystrophin gene.

Abstract: A seawater corrosion-resistant marine engineering steel and a preparation method thereof are provided. The seawater corrosion-resistant marine engineering steel consists of the following chemical compositions in percentage by mass: C: 0.011-0.069%, Si: 0.11-0.29%, Cr: 1.51-1.99%, Nb: 0.02-0.05%, Zr: 0.01-0.02%, RE: 0.0034-0.02%, and the balance of Fe and inevitable impurities. The mass percentages of Zr element and RE element also satisfy the following formulas: 0.01%<Zr+RE<0.02%, and Zr/RE=1-3. The marine engineering steel is designed with cheap chemical compositions of low carbon, low silicon and medium chromium, and is completely free of valuable corrosion-resistant metal elements such as Ni and Cu. Instead of the traditional Al deoxidization technology, Si deoxidization assisted by Zr?RE composite deoxidization is used to form a fine, dispersed and uniform composite oxysulfide.

Abstract: An apparatus configured to treat wastewater includes a first water tank configured to store wastewater, a second water tank configured to store absorbent liquid, and a membrane assembly including a membrane including holes, the membrane assembly configured to receive the wastewater from the first water tank and the absorbent liquid from the second water tank, where the membrane assembly is further configured to allow materials to move between the wastewater and the absorbent liquid through the holes, and where, in the membrane assembly, a temperature of the absorbent liquid is different from a temperature of the wastewater.

Abstract: The new blueberry plant ‘FC13-113’ is provided. ‘FC13-113’ is a commercial variety intended for the hand harvest fresh fruit market. The variety is produced from a cross of ‘ZF06-231’ (female parent, unpatented) and ‘ZF08-189’ (male parent, unpatented), which can be distinguished by its very large, high-quality fruit in the late season. Compared to other high chill varieties in this ripening window known to the Inventors, the fruit is much larger. The berry is very oblate with a distinct wide calyx. The plant is upright with medium vigor and high productivity.